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   How does the IARC select a carcinogenic agent?

   • The IARC staff makes the final selection of agents for review by taking into account the prevalence and intensity of exposure (of both occupational groups and the general population) and availability of sufficient literature for an evaluation of carcinogenicity, as well as advice from the Advisory Groups.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   Which environmental factors are carcinogenic to humans?

   • The IARC Monographs identify environmental factors that are carcinogenic hazards to humans. These include chemicals, complex mixtures, occupational exposures, physical agents, biological agents, and lifestyle factors.

   IARC Monographs – General Information

   monographs.iarc.who.int/home/iarc-monographs-general-information/

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   What are IARC monographs used for?

   • IARC Monographs are widely used to identify potential carcinogenic hazards to humans and serve as reference documents summarizing the literature on many different agents.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   What are IARC assessments of carcinogenicity based on?

   • IARC assessments of carcinogenicity are based on, and necessarily limited to, scientific evidence available at the time of the review. The evidence comes from epidemiologic studies, animal bioassays, pharmacokinetic/mechanistic experiments, and surveys of human exposure.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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2. monographs.iarc.who.int › agents-classified-by-theAgents Classified by the IARC Monographs , Volumes 1–135

   monographs.iarc.who.int › agents-classified-by-the

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   Dec 1, 2023 · Carcinogenic to humans: 128 agents: Group 2A: Probably carcinogenic to humans 95 agents: Group 2B: Possibly carcinogenic to humans: 323 agents: Group 3: Not classifiable as to its carcinogenicity to humans: 500 agents

   • List of Classifications

     List of Classifications – IARC Monographs on the...

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     Maternal orphans due to cancer: the intergenerational impact...

3. www.ncbi.nlm.nih.gov › pmc › articlesIARC Monographs: 40 Years of Evaluating Carcinogenic Hazards ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Feb 24, 2015 · In the 111 volumes of the Monographs produced over the four decades since 1971, 970 agents have been considered, 114 (12%) have been classified as carcinogenic to humans (Group 1), 69 (7%) as probably carcinogenic (Group 2A), 283 (29%) as possibly carcinogenic (Group 2B), 504 (52%) as not classifiable regarding their carcinogenicity (Group 3 ...

   • Author: Neil Pearce, Aaron Blair, Paolo Vineis, Wolfgang Ahrens, Aage Andersen, Josep M. Anto, Bruce K. Arms...

   • Publish Year: 2015

4. monographs.iarc.who.int › home › iarc-monographsIARC Monographs – General Information – IARC Monographs on ...

   monographs.iarc.who.int › home › iarc-monographs

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   The IARC Monographs identify environmental factors that are carcinogenic hazards to humans. These include chemicals, complex mixtures, occupational exposures, physical agents, biological agents, and lifestyle factors.

5. www.ncbi.nlm.nih.gov › pmc › articlesThe IARC Monographs: Updated Procedures for Modern and ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Sep 9, 2019 · Slightly more than half of all agents evaluated have been classified as possibly carcinogenic, probably carcinogenic, or carcinogenic to humans ( https://Monographs.iarc.fr/agents-classified-by-the-iarc/ ). The IARC Monographs embody principles of scientific rigor, impartial evaluation, transparency, and consistency.

   • Author: Jonathan M Samet, Weihsueh A Chiu, Vincent Cogliano, Jennifer Jinot, David Kriebel, Ruth M Lunn, Fre...

   • Publish Year: 2020

6. www.ncbi.nlm.nih.gov › books › NBK294452IARC Monographs on the Identification of Carcinogenic Hazards ...

   www.ncbi.nlm.nih.gov › books › NBK294452

   The IARC Monographs identify the preventable causes of human cancer. These include chemicals, physical and biological agents, pharmaceuticals, complex mixtures, occupational exposures, and other exposures of everyday life (e.g. lifestyle factors).