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Since its establishment in the early 1970s, the IARC Monographs Programme has evaluated more than 1000 agents with evidence of human exposure and for which some suspicion exists of an increased cancer risk to humans. The IARC Monographs Programme has developed detailed criteria against which to evaluate the available scientific evidence on the carcinogenic potential of such agents. These ...
What was the scientific basis of the IARC evaluations? The pesticides tetrachlorvinphos and parathion were classified as possibly carcinogenic to humans (Group 2B) based on convincing evidence that these agents cause cancer in laboratory animals. For the insecticide , there is malathion limited evidence of carcinogenicity in humans for nonHodgkin -
When, based on mechanistic considerations, the agent belongs to a class of agents of which one or more is probably carcinogenic to humans (Group 2A) or carcinogenic to humans (Group 1). These scenarios may also occur simultaneously within a Group 2A classification. Group 2B: The agent is possibly carcinogenic to humans.
Sep 9, 2019 · Cancer in humans: Possibly carcinogenic to humans (group 2B) Inadequate: Sufficient: Not necessary: Cancer in experimental animals: Inadequate: Less than sufficient: Strong: key characteristics of carcinogens: Mechanistic evidence: Limited: Sufficient: Strong: the mechanism of carcinogenicity in experimental animals does not operate in humans†
Jun 10, 2012 · The International Agency for Research on Cancer (IARC) has listed cobalt and cobalt compounds within group 2B (agents which are possibly carcinogenic to humans). Metallic cobalt and bivalent cobalt oxide was found to be carcinogenic in experimental animals (rats) at a relatively high dose, by route(s), histologic type(s) or by mechanism(s) that ...
Human Cancer: Known Causes and Prevention by Organ Site This poster presents carcinogenic agents and cancer-preventive interventions by organ site READ MORE
Jun 29, 2023 · IARC have, however, now changed the name to “IARC Monographs on the Identification of Carcinogenic Hazards to Humans”, which at least describes what they actually do. And at least, this time, there will be a risk assessment published by JEFCA, at the same time as the IARC assessment.
