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    • What does IARC mean by possible carcinogenic to humans?

      • IARC defines a Group 2B classification as “the agent is possible carcinogenic to humans.” This category is used by IARC when there is limited scientific evidence that a compound increases cancer risk in humans and less than sufficient evidence of an increased cancer risk in experimental animals.
  1. Oct 19, 2020 · IARC defines a Group 2B classification as “the agent is possibly carcinogenic to humans.”. This category is used by IARC when there is only limited scientific evidence in human studies that a compound increases cancer risk in humans and when there is sufficient evidence of an increased cancer risk in experimental animals.

  2. animals. Agents are assigned to either Group 2A (probably carcinogenic to humans) or Group 2B (possibly carcinogenic to humans) on the basis of epidemiological and experimental evidence of carcinogenicity and mechanistic and other relevant data. The terms probably carcinogenic and possibly carcinogenic have no quantitative significance and are ...

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    What does IARC mean by possible carcinogenic to humans?

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  4. Cupferron was classified as possibly carcinogenic to humans (Group 2B). The classification was based on: . sufficient evidence of carcinogenicity in experimental animals . strong evidence in experimental systems that cupferron exhibits essential properties of human carcinogens (called key characteristics of carcinogens); cupferron is genotoxic.

  5. animals and strong mechanistic evidence in human cells or tissues. Group 2B: The agent is possibly carcinogenic to humans This category is generally used when only one of the following evaluations has been made by the Working

  6. Oct 26, 2015 · Red meat, meanwhile, was placed into group 2A. This group is for substances defined as ‘probably carcinogenic to humans’; this means that the evidence in humans is still somewhat limited, but there is sufficient evidence in experimental animals of the substance’s carcinogenic nature. As the evidence decreases, so does the ranking.

  7. Group 2B: "Possibly carcinogenic to humans" There is some evidence that it can cause cancer in humans but at present it is far from conclusive. IARC definition and list of compounds . Group 3: "Unclassifiable as to carcinogenicity in humans" There is no evidence at present that it causes cancer in humans. IARC definition and list of compounds