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  1. Oct 19, 2020 · IARC defines a Group 2B classification as “the agent is possibly carcinogenic to humans.”. This category is used by IARC when there is only limited scientific evidence in human studies that a compound increases cancer risk in humans and when there is sufficient evidence of an increased cancer risk in experimental animals.

  2. animals. Agents are assigned to either Group 2A (probably carcinogenic to humans) or Group 2B (possibly carcinogenic to humans) on the basis of epidemiological and experimental evidence of carcinogenicity and mechanistic and other relevant data. The terms probably carcinogenic and possibly carcinogenic have no quantitative significance and are ...

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  4. animals and strong mechanistic evidence in human cells or tissues. Group 2B: The agent is possibly carcinogenic to humans This category is generally used when only one of the following evaluations has been made by the Working

  5. IARC classifications. The International Agency for Research on Cancer (IARC) have devised a system of categories to evaluate the carcinogenicity of an agent to humans. An agent is classified based on scientific evidence derived from human and experimental animal studies and from mechanistic and other relevant data.

  6. Group 2B: "Possibly carcinogenic to humans" There is some evidence that it can cause cancer in humans but at present it is far from conclusive. IARC definition and list of compounds . Group 3: "Unclassifiable as to carcinogenicity in humans" There is no evidence at present that it causes cancer in humans. IARC definition and list of compounds

  7. Nov 17, 2021 · See Preventable Exposures Associated With Human Cancers (Cogliano et al., 2011) Read the IARC Monographs Q&A for answers to commonly asked questions on the evaluation process. Although care was taken in preparing these lists, mistakes may be present. If you find an error, please notify us at Last update: 17 November 2021