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Jun 29, 2023 · Listing aspartame as a possible carcinogen is intended to motivate more research, said the sources close to the IARC, which will help agencies, consumers and manufacturers draw firmer conclusions.
Jun 3, 2021 · In animals and humans, the metabolite of aflatoxins responsible for their carcinogenic properties is the short-lived AFB-2,3-epoxide, currently known as AFB1-8,9-epoxide (AFBO), which has the capacity to form adducts with DNA and proteins and results in mutations [29,59]. Cytochromes P-450 3A4 and 1A2 are major liver enzymes that are ...
Since its establishment in the early 1970s, the IARC Monographs Programme has evaluated more than 1000 agents with evidence of human exposure and for which some suspicion exists of an increased cancer risk to humans. The IARC Monographs Programme has developed detailed criteria against which to evaluate the available scientific evidence on the carcinogenic potential of such agents. These ...
Nov 14, 2023 · Group B - Probably Carcinogenic to Humans: Agents with sufficient evidence (i.e., indicative of a causal relationship) from animal bioassay data, but either limited human evidence (i.e., indicative of a possible causal relationship, but not exclusive of alternative explanations; Group B1), or with little or no human data (Group B2). Group C ...
Human Cancer: Known Causes and Prevention by Organ Site This poster presents carcinogenic agents and cancer-preventive interventions by organ site READ MORE
May 19, 2016 · Group 1: Definitely carcinogenic to humans. Some examples include arsenic, asbestos, Hepatitis B, Hepatitis C, Plutonium, processed meat, and Ultraviolet Radiation. Group 2A: Probably carcinogenic to humans. There isn’t enough evidence to definitively conclude that these substances cause cancer, but there’s enough to warrant the warning label.
Most of the individual PAHs classified by IARC as either probably carcinogenic to humans (Group 2A) or possibly carcinogenic to humans (Group 2B) (listed above) are genotoxic and have been shown to cause skin cancer and/or be initiators of skin cancer in rodents (IARC, 1983, 2010).