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1. • • IARC group 2B substances, mixtures and exposure circumstances are those that have been classified as "possibly carcinogenic to humans" by the International Agency for Research on Cancer (IARC) as This category is used when there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals.
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     IARC group 2B - Wikipedia

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   How does the IARC select a carcinogenic agent?

   • The IARC staff makes the final selection of agents for review by taking into account the prevalence and intensity of exposure (of both occupational groups and the general population) and availability of sufficient literature for an evaluation of carcinogenicity, as well as advice from the Advisory Groups.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   What are IARC assessments of carcinogenicity based on?

   • IARC assessments of carcinogenicity are based on, and necessarily limited to, scientific evidence available at the time of the review. The evidence comes from epidemiologic studies, animal bioassays, pharmacokinetic/mechanistic experiments, and surveys of human exposure.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

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   What are IARC monographs used for?

   • IARC Monographs are widely used to identify potential carcinogenic hazards to humans and serve as reference documents summarizing the literature on many different agents.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   How many carcinogenic agents have been evaluated?

   • The principles, procedures, and scientific criteria that guide the evaluations are described in the Preamble to the IARC Monographs. Since 1971, more than 1000 agents have been evaluated, of which more than 500 have been identified as carcinogenic, probably carcinogenic, or possibly carcinogenic to humans.

   IARC Monographs – General Information

   monographs.iarc.who.int/home/iarc-monographs-general-information/

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3. monographs.iarc.who.int › home › iarc-monographsIARC Monographs – General Information – IARC Monographs on ...

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   Since 1971, more than 1000 agents have been evaluated, of which more than 500 have been identified as carcinogenic, probably carcinogenic, or possibly carcinogenic to humans. Read the IARC Monographs Q&A for answers to commonly asked questions on the evaluation process.

4. www.ncbi.nlm.nih.gov › pmc › articlesIARC Monographs: 40 Years of Evaluating Carcinogenic Hazards ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Feb 24, 2015 · The terms probably carcinogenic and possibly carcinogenic have no quantitative significance and are used simply as descriptors of different levels of evidence of human carcinogenicity, with probably carcinogenic signifying a higher level of evidence than possibly carcinogenic.

   • Author: Neil Pearce, Aaron Blair, Paolo Vineis, Wolfgang Ahrens, Aage Andersen, Josep M. Anto, Bruce K. Arms...

   • Publish Year: 2015

5. www.ncbi.nlm.nih.gov › pmc › articlesThe IARC Monographs: Updated Procedures for Modern and ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Sep 9, 2019 · The agent is possibly carcinogenic to humans (group 2B): This category generally applies when only one of the following evaluations has been made by the working group: • Limited evidence of carcinogenicity in humans

   • Author: Jonathan M Samet, Weihsueh A Chiu, Vincent Cogliano, Jennifer Jinot, David Kriebel, Ruth M Lunn, Fre...

   • Publish Year: 2020

6. www.who.int › publications › mIARC Monographs on the Evaluation of Carcinogenic Risks to ...

   www.who.int › publications › m

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   Nov 14, 2012 · Overview. Volume 100 of the IARC Monographs, A Review of Human Carcinogens, covers all agents previously classified by IARC as "carcinogenic to humans (Group 1)" and was developed by six separate Working Groups: Pharmaceuticals; Biological agents; Arsenic, Metals, Fibres, and Dusts; Radiation; Personal Habits and Indoor Combustions; Chemical ...

7. www.cancer.org › cancer › risk-preventionDetermining if Something Is a Carcinogen | American Cancer ...

   www.cancer.org › cancer › risk-prevention

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   Group 1: Carcinogenic to humans; Group 2A: Probably carcinogenic to humans; Group 2B: Possibly carcinogenic to humans; Group 3: Not classifiable as to its carcinogenicity in humans; Perhaps not surprisingly, based on how hard it can be to test possible carcinogens, most are listed as being of probable, possible, or unknown risk.

8. www.iarc.who.int › infographics › iarc-monographsIARC Monographs hazard classification – IARC

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   Jun 16, 2023 · 16 June 2023. IARC Monographs hazard classification. This infographic presents the categories used by the IARC Monographs on the Identification of Carcinogenic Hazards to Humans to classify a substance according to the level of certainty that the substance can cause cancer.

9. monographs.iarc.who.int › agents-classified-by-theAgents Classified by the IARC Monographs , Volumes 1–135

   monographs.iarc.who.int › agents-classified-by-the

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   Dec 1, 2023 · Carcinogenic to humans: 128 agents: Group 2A: Probably carcinogenic to humans 95 agents: Group 2B: Possibly carcinogenic to humans: 323 agents: Group 3: Not classifiable as to its carcinogenicity to humans: 500 agents