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   How does the IARC select a carcinogenic agent?

   • The IARC staff makes the final selection of agents for review by taking into account the prevalence and intensity of exposure (of both occupational groups and the general population) and availability of sufficient literature for an evaluation of carcinogenicity, as well as advice from the Advisory Groups.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

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   What are IARC assessments of carcinogenicity based on?

   • IARC assessments of carcinogenicity are based on, and necessarily limited to, scientific evidence available at the time of the review. The evidence comes from epidemiologic studies, animal bioassays, pharmacokinetic/mechanistic experiments, and surveys of human exposure.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   What are IARC monographs used for?

   • IARC Monographs are widely used to identify potential carcinogenic hazards to humans and serve as reference documents summarizing the literature on many different agents.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   What does IARC stand for?

   • For nearly 50 years, the Monograph s program of the International Agency for Research on Cancer (IARC) has been a premier global resource for identifying agents that can cause cancer. The identification of carcinogenic hazards is a necessary initial step in cancer prevention.

   The IARC Monographs: Updated Procedures for Modern and Transparent

   www.ncbi.nlm.nih.gov/pmc/articles/PMC6968684/

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2. monographs.iarc.who.int › wp-content › uploadsQuestions and Answers - monographs.iarc.who.int

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   The IARC Monographs Programme seeks to identify agents that are cancer hazards, meaning they pose the potential for the exposure to cause cancer. However, the classification does not indicate the level of risk associated with a given level or circumstance of exposure. The cancer risk associated with substances or agents assigned the same ...

3. monographs.iarc.who.int › home › iarc-monographsIARC Monographs – General Information – IARC Monographs on ...

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   Since 1971, more than 1000 agents have been evaluated, of which more than 500 have been identified as carcinogenic, probably carcinogenic, or possibly carcinogenic to humans. Read the IARC Monographs Q&A for answers to commonly asked questions on the evaluation process.

4. www.iarc.who.int › questions-and-answersQuestions and Answers – IARC - International Agency for ...

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   IARC Monographs evaluate the carcinogenicity of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) Questions and Answers (Q&A) for Methyleugenol and Isoeugenol. Aspartame. IARC Monographs on the Identification of Carcinogenic Hazards to Humans.

5. www.ncbi.nlm.nih.gov › pmc › articlesThe IARC Monographs: Updated Procedures for Modern and ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Sep 9, 2019 · Slightly more than half of all agents evaluated have been classified as possibly carcinogenic, probably carcinogenic, or carcinogenic to humans ( https://Monographs.iarc.fr/agents-classified-by-the-iarc/ ). The IARC Monographs embody principles of scientific rigor, impartial evaluation, transparency, and consistency.

   • Author: Jonathan M Samet, Weihsueh A Chiu, Vincent Cogliano, Jennifer Jinot, David Kriebel, Ruth M Lunn, Fre...

   • Publish Year: 2020

6. monographs.iarc.who.int › agents-classified-by-theAgents Classified by the IARC Monographs , Volumes 1–135

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   Dec 1, 2023 · Group 2B. Possibly carcinogenic to humans. 323 agents. Group 3. Not classifiable as to its carcinogenicity to humans. 500 agents. For definitions of these groups, please see the Preamble.

7. www.ncbi.nlm.nih.gov › pmc › articlesIARC Monographs: 40 Years of Evaluating Carcinogenic Hazards ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Feb 24, 2015 · The terms probably carcinogenic and possibly carcinogenic have no quantitative significance and are used simply as descriptors of different levels of evidence of human carcinogenicity, with probably carcinogenic signifying a higher level of evidence than possibly carcinogenic.

8. www.who.int › publications › mIARC Monographs on the Evaluation of Carcinogenic Risks to ...

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   Overview. Volume 100 of the IARC Monographs, A Review of Human Carcinogens, covers all agents previously classified by IARC as "carcinogenic to humans (Group 1)" and was developed by six separate Working Groups: Pharmaceuticals; Biological agents; Arsenic, Metals, Fibres, and Dusts; Radiation; Personal Habits and Indoor Combustions; Chemical ...