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What causes morbilliform drug eruption? Morbilliform drug eruption is a form of allergic reaction. It is mediated by cytotoxic T-cells and classified as a Type IV immune reaction. The target of attack may be drug, a metabolite of the drug, or a protein bonded to the drug.
Mar 13, 2019 · The term “morbilliform” connotes a measles-like: the rash of measles is classically described as having macules that are 3 to 4 mm in size that coalesce. MDE is usually itchy. The eruption usually begins on the trunk and upper extremities and progresses caudally. It is usually symmetric.
Jan 12, 2023 · INTRODUCTION. Exanthematous (maculopapular) drug eruption, also called morbilliform (measles-like) drug-induced exanthem, is the most common drug hypersensitivity reaction [ 1,2 ].
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Apr 26, 2022 · Morbilliform drug eruption is a rash that develops because of an adverse reaction to a drug. Antibiotics are the usual trigger, but many drugs can trigger this allergic reaction.
Mar 8, 2021 · Key Concepts # Exanthematous (morbilliform) drug eruptions are the most common type of adverse drug reaction. Thought to be delayed-type, T cell-mediated immune reaction. Characterized by erythematous macules and papules coalescing into patches and plaques without secondary change that predominantly involve the trunk and proximal extremities.
They are raised, swollen, red or flesh-colored bumps or welts that appear on the skin. They can take on many shapes and can be very itchy. They usually develop in groups and may cover large areas of skin. Hives can affect any part of the body. Most of the time, hives indicate an allergic reaction.
Drug rashes. Aziz Khan, ... Jane M. Grant-Kels, in Dermatology for the Primary Care Provider, 2022. Clinical features. Morbilliform drug eruption, also called “exanthematous” or “maculopapular drug eruption,” is the most common form of cutaneous drug eruption, accounting for more than 80% of drug eruptions. •.
