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  1. Pyrexia is the medical term for fever, in which the human body temperature rises above the average normal (37 degrees Celsius or 98.6 degrees Fahrenheit). Pyrexia is one of the most common symptoms of numerous medical conditions. Read on to know the causes, symptoms, and treatment of pyrexia.

  2. Sep 4, 2023 · Introduction. Fever, or pyrexia, is the elevation of an individual's core body temperature above a 'set-point' regulated by the body's thermoregulatory center in the hypothalamus. This increase in the body's 'set-point' temperature is often due to a physiological process brought about by infectious causes or non-infectious causes such as ...

    • 2022/09/11
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    • Temperature Target
    • Efficacy and Risks of Antipyretic Methods
    • Paracetamol
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    • Surface Cooling Devices
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    • Thermal Tolerance of Cooling

    Different approaches to fever treatment have been proposed: 1. Control of pyrexia when it occurs: treatment administered when temperature exceeds a predefined threshold 2. Strict avoidance of pyrexia: temperature maintained below fever threshold 3. Strict maintenance of normothermia: TTM with a predefined normothermia range, e.g., 36–37 °C. The abs...

    Antipyretic agents, mainly paracetamol and NSAIDs, and physical cooling methods can be used to control pyrexia. Cooling with surface devices is usually preferred for fever control while endovascular methods are more commonly restricted to therapeutic hypothermia. Infusions of cold fluids are easy to administer and inexpensive but this strategy expo...

    Paracetamol is the most commonly administered antipyretic in clinical practice . Compared with placebo or no treatment, the difference in body temperature usually reaches statistical significance, although this is modest with uncertain clinical significance. In patients with brain injury, a standard dose (3 g/day) of paracetamol is often reported a...

    NSAIDs are regularly used in the ICU despite the lack of adequate safety evaluation. NSAIDs have a well known side effect profile including hypotension, impaired hepatic and renal function, sodium and water retention, gastrointestinal bleeding and platelet dysfunction. In an attempt to avoid some of these effects, low dose continuous infusion of di...

    Three main types of surface cooling devices are available: air-circulating blankets, water circulating blankets and hydrogel-coated water-circulating pads . There is no evidence to support the use of fans for temperature control. Fans are usually considered to help with patient comfort but they can induce shivering . In febrile ICU patients, air-ci...

    Several intravenous heat exchange catheter devices are available for temperature management . Endovascular cooling was initially evaluated for therapeutic hypothermia. Some controlled studies are now available in patients with acute brain injury managed with controlled normothermia. The obvious disadvantage is their associated risks, which are like...

    Any decrease in core and/or peripheral temperature will result in vasoconstriction followed by shivering. In normal and febrile conditions, shivering commences at a body core temperature of ≈1.5 °C under the hypothalamic set point . Skin temperature accounts for around 20 % of thermoregulation and cold stress can promote shivering while the core te...

    • James F. Doyle, Frédérique Schortgen
    • 2016
  4. Jul 7, 2023 · ‌Hyperpyrexia is a condition where the body temperature goes above 106.7 degrees Fahrenheit (41.5 degrees Celsius) due to changes in the hypothalamus — the organ in the...

  5. May 3, 2018 · Symptoms. Causes. Treatment. Outlook. What is hyperpyrexia? Normal body temperature is typically 98.6°F (37°C). However, slight fluctuations can occur throughout the day. For example, your...

  6. Sep 1, 2016 · The absolute body temperature and the response to pharmacological anti-pyretic therapy are often useful in distinguishing between hyperthermia and pyrexia. A temperature that exceeds 41.0 °C and is not responsive to pharmacologic anti-pyretic therapy is more commonly observed in patients with hyperthermia.

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