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Pyrexia is the medical term for fever, in which the human body temperature rises above the average normal (37 degrees Celsius or 98.6 degrees Fahrenheit). Pyrexia is one of the most common symptoms of numerous medical conditions. Read on to know the causes, symptoms, and treatment of pyrexia.
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- Temperature Target
- Efficacy and Risks of Antipyretic Methods
- Paracetamol
- Non-Steroidal Anti-Inflammatory Agents
- Surface Cooling Devices
- Endovascular Cooling Devices
- Thermal Tolerance of Cooling
Different approaches to fever treatment have been proposed: 1. Control of pyrexia when it occurs: treatment administered when temperature exceeds a predefined threshold 2. Strict avoidance of pyrexia: temperature maintained below fever threshold 3. Strict maintenance of normothermia: TTM with a predefined normothermia range, e.g., 36–37 °C. The abs...
Antipyretic agents, mainly paracetamol and NSAIDs, and physical cooling methods can be used to control pyrexia. Cooling with surface devices is usually preferred for fever control while endovascular methods are more commonly restricted to therapeutic hypothermia. Infusions of cold fluids are easy to administer and inexpensive but this strategy expo...
Paracetamol is the most commonly administered antipyretic in clinical practice . Compared with placebo or no treatment, the difference in body temperature usually reaches statistical significance, although this is modest with uncertain clinical significance. In patients with brain injury, a standard dose (3 g/day) of paracetamol is often reported a...
NSAIDs are regularly used in the ICU despite the lack of adequate safety evaluation. NSAIDs have a well known side effect profile including hypotension, impaired hepatic and renal function, sodium and water retention, gastrointestinal bleeding and platelet dysfunction. In an attempt to avoid some of these effects, low dose continuous infusion of di...
Three main types of surface cooling devices are available: air-circulating blankets, water circulating blankets and hydrogel-coated water-circulating pads . There is no evidence to support the use of fans for temperature control. Fans are usually considered to help with patient comfort but they can induce shivering . In febrile ICU patients, air-ci...
Several intravenous heat exchange catheter devices are available for temperature management . Endovascular cooling was initially evaluated for therapeutic hypothermia. Some controlled studies are now available in patients with acute brain injury managed with controlled normothermia. The obvious disadvantage is their associated risks, which are like...
Any decrease in core and/or peripheral temperature will result in vasoconstriction followed by shivering. In normal and febrile conditions, shivering commences at a body core temperature of ≈1.5 °C under the hypothalamic set point . Skin temperature accounts for around 20 % of thermoregulation and cold stress can promote shivering while the core te...
- James F. Doyle, Frédérique Schortgen
- 2016
Nov 21, 2023 · What does pyrexia mean? Pyrexia is derived from Greek origin meaning presence of fever or to be feverish. The normal body temperature is 98.6F, and any temperature above 100.4F is considered a fever.
- What are the symptoms of pyrexia?Some common symptoms of pyrexia include: increased body temperature, irritability, dehydration, muscle aches, headaches, loss of appetite, weakness...
- What causes pyrexia?Some of the common causes of pyrexia include infection, anesthetic agents, side effects from medicinal and recreational drugs such as SSRIs, thyroi...
- What is a pyrexia temperature?The typical temperature for pyrexia diagnosis is any body temperature above 100.4 degrees F. Hyperpyrexia is extremely elevator fever with temperat...
- What is the difference between fever and pyrexia?Fever is any elevation in body temperature above normal body temperature of 98.6 degrees F, whereas pyrexia is typically anything above 100.4 degre...
Classic adult pyrexia of unknown origin is fever of 38.3°C or greater for at least 3 weeks with no identified cause after three days of hospital evaluation or three outpatient visits Common causes are infections, neoplasms, and connective tissue disorders A thorough history and physical examination, along with basic investigations will usually
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Sep 1, 2016 · Elevation in core body temperature is one of the most frequently detected abnormal signs in patients admitted to adult ICUs, and is associated with increased mortality in select populations of critically ill patients. The definition of an elevated body temperature varies considerably by population and thermometer, and is commonly defined by a temperature of 38.0 °C or greater. Terms such as ...
Nov 20, 2021 · Pyrexia (fever) refers to an abnormal increase in temperature occurring under central nervous system control as a component of a co-ordinated biological response. The average normal temperature is usually quoted as 37 °C (98.6 °F) [ 1, 2 ], a value arrived at following research conducted in the 1800s. Newer research involving oral measurement ...
