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  1. Sep 4, 2023 · Fevers are typically managed with antipyretics, which work by inhibiting the enzyme cyclooxygenase (COX), thereby reducing the levels of PGE2 within the hypothalamus. Other mechanisms of antipyretics have been suggested, which include reduction in proinflammatory mediators and enhancement of anti-inflammatory signals at the site of injury.

    • 2022/09/11
  2. Oct 3, 2016 · Pyrexia (also named fever) is the altering upward of the thermoregulatory set point, often secondary to the systemic inflammatory response to a stimulus such as infection. The molecular basis is summarized in Fig. 1 [5, 6].

    • James F. Doyle, Frédérique Schortgen
    • 10.1186/s13054-016-1467-2
    • 2016
    • Crit Care. 2016; 20: 303.
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  4. Oct 15, 2010 · Summary points. Classic adult pyrexia of unknown origin is fever of 38.3°C or greater for at least 3 weeks with no identified cause after three days of hospital evaluation or three outpatient visits. Common causes are infections, neoplasms, and connective tissue disorders.

    • George M Varghese, Paul Trowbridge, Tom Doherty
    • 2010
  5. Pyrexia: An update on importance in clinical practice. Pyrexic patients are usually attended with some scepticism by anaesthesiologists. Main reasons are the absence of comprehensible guidelines pertaining to anaesthesia in such patients and the presence of innumerable aetiologies of pyrexia. This article has tried to fill the existing void in ...

    • Ragi Jain, Deepesh Saxena
    • 10.4103/0019-5049.154996
    • 2015
    • Indian J Anaesth. 2015 Apr; 59(4): 207-211.
  6. Pyrexia is the medical term for fever, in which the human body temperature rises above the average normal (37 degrees Celsius or 98.6 degrees Fahrenheit). Pyrexia is one of the most common symptoms of numerous medical conditions. Read on to know the causes, symptoms, and treatment of pyrexia.

  7. Sep 1, 2016 · 51 Citations. 38 Altmetric. Metrics. Abstract. Elevation in core body temperature is one of the most frequently detected abnormal signs in patients admitted to adult ICUs, and is associated with increased mortality in select populations of critically ill patients.

  8. Nov 15, 2023 · Fever in adults: When to worry ... Severe stomach pain or persistent vomiting; Skin rashes, blisters, or a red streak on an arm or leg; A severe sore throat, swelling of the throat, or earache;

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