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What causes pyrexia?
What is fever & pyrexia?
How is pyrexia of unknown origin evaluated?
Sep 4, 2023 · Fever, or pyrexia, is the elevation of an individual's core body temperature above a 'set-point' regulated by the body's thermoregulatory center in the hypothalamus. This increase in the body's 'set-point' temperature is often due to a physiological process brought about by infectious causes or non-infectious causes such as inflammation ...
Jul 14, 2016 · Fever has its etymological basis in Latin, meaning simply ‘heat’, and pyrexia comes from the Greek ‘pyr’, meaning fire or fever. Some sources use the terms interchangeably, whereas others preserve ‘fever’ to mean a raised temperature caused by the action of thermoregulatory pyrogens on the hypothalamus; for instance, in sepsis and ...
- Edward James Walter, Sameer Hanna-Jumma, Mike Carraretto, Lui Forni
- 10.1186/s13054-016-1375-5
- 2016
- Crit Care. 2016; 20: 200.
- Neonates
- Prenatal History
- Household Contacts
- Review of Systems and Physical Examination
- History and Examination in Young Infants
- History and Examination in Children Aged Between 3 Months and 3 Years
It is vital to obtain a full history for any neonate suffering from pyrexia. The pattern of symptoms may point to an infective focus (e.g. diarrhoea, coughing) or be more general (e.g. not feeding, being irritable, lethargy). 20–50% of neonates with meningitis have a convulsion. It needs to be established if there is anyone in contact with the chil...
The pregnancy history should be reviewed, encompassing any sexually transmitted infection, such as HIV, hepatitis B or C, treponemal infection, gonorrhoea, chlamydia or herpes simplex. The mother’s GBS status should be reviewed, together with any precautions taken, how the delivery occurred, if the membranes were ruptured long before birth and whet...
Any family members suffering from illness need to be recorded. If the patient has been in contact with animals at home or elsewhere (such as at a nursery), this should also be ascertained. The vaccination histories of others living in the house should be documented. If another pregnancy has been lost or a baby has previously died due to an infectio...
All body systems need to be carefully reviewed for symptoms to pick up any clues about the origin of pyrexia. Patients should be completely examined and vital signs noted. Oximetry should be performed, and growth checked, with the various parameters assigned to the appropriate percentile. On general examination, note how active the child is, whethe...
As with a neonate, pyrexia in an infant may be reflected in symptoms pointing to an infective focus (diarrhoea or coughing) or be more general (e.g. not feeding, being irritable, lethargy). Identify if the infant has been in contact with anyone else suffering from illness at home or outside, such as at a nursery. Recent illness, vaccinations admini...
History taking needs to concentrate on factors that put an infant or toddler at higher risk of severe bacterial infection.
Oct 15, 2010 · Pyrexia of unknown origin has a wide differential diagnosis. The most frequently encountered underlying causes of the pyrexia are listed in box 2. Broadly speaking, the three most common causes are infection, neoplasia, and connective tissue disease.
- George M Varghese, Paul Trowbridge, Tom Doherty
- 2010
Classic adult pyrexia of unknown origin is fever of 38.3°C or greater for at least 3 weeks with no identified cause after three days of hospital evaluation or three outpatient visits Common causes are infections, neoplasms, and connective tissue disorders.
Jul 12, 2022 · Fever, or pyrexia, can be defined as having a temperature above the normal range owing to an increase in the body’s core temperature setpoint. 1 2 The thermoregulatory centre, located in the hypothalamus, contains temperature sensitive neurons, aiming to maintain thermal homoeostasis.
