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  1. Neonatal Sepsis is an emergency. Earliest clinical features includes refusal to feed, feed intolerance, hypothermia, excessive cry or lethargy, respiratory distress and increased CFT.

  2. INTRODUCTION. Neonatal sepsis is a systemic infection occurring in infants at ≤28 days of life and is an important cause of morbidity and mortality of newborns ().Early-onset neonatal sepsis (EOS) has been variably defined based on the age at onset, with bacteremia or bacterial meningitis occurring at ≤72 h in infants hospitalized in the neonatal intensive care unit (NICU), versus <7 days ...

    • Kari A. Simonsen, Ann L. Anderson-Berry, Shirley F. Delair, H. Dele Davies
    • 852
    • 2014
  3. In a prospective cohort, we measured inflammatory cytokines as a potential biomarker for neonatal sepsis. Methods: Serum inflammatory cytokine levels were evaluated in the early stage of neonatal sepsis and after antimicrobial treatment. Receiver operating characteristic curves assessed the diagnostic value of cytokines.

    • Qing Ye, Li-Zhong Du, Wen-Xia Shao, Shi-Qiang Shang
    • 20
    • 2017
  4. Jun 19, 2019 · Neonatal sepsis is a diagnosis made in infants less than 28 days of life and consists of a clinical syndrome that may include systemic signs of infection, circulatory shock, and multisystem organ failure. Neonatal sepsis may be divided into two types: early-onset neonatal sepsis (EONS) and late-onset neonatal sepsis (LONS).

  5. effects and also the emergence of drug resistant microorganisms. Neonatal sepsis can be early or late and most of the cases of early sepsis are within 24 hours (4). As the immune system of neonates is weak, they are more susceptible to invasive infections. Premature infants are even more prone to infections than term neonates (5).

  6. What is/are the earliest predictor(s) of neonatal sepsis? The findings suggest that maternal platelet parameters (MPV, PCT and IPF) can be utilized as evidence of early predictors of development of neonatal sepsis and respiratory distress and may be considered as a predictive markers for adverse neonatal outcome.

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