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- Morbilliform eruptions tend to present with diffuse papules coalescing into plaques. In darker skin, these papules are often violaceous to dark brown with minimal to no visible background erythema. In contrast, lighter skin tends to show bright pink to red papules with a marked background of erythema.
Mar 22, 2024 · Most reactions are mild, accompanied by pruritus, and resolve promptly after the offending drug is discontinued. Drug eruptions can mimic virtually all the morphologic expressions in dermatology and must be the first consideration in the differential diagnosis of a suddenly appearing eruption.
Apr 5, 2024 · Maculopapular or morbilliform drug eruptions are the most common cutaneous adverse drug reaction in children, characterized by generalized erythematous macules and/or papules. It is a form of delayed T-cell hypersensitivity reaction (Type IV).
Mar 24, 2024 · INSIGHT. In the appropriate clinical setting, an exanthematous drug reaction, a viral exanthem, and acute graft-versus-host disease (GVHD) are all clinically and histologically indistinguishable. SYNONYMS Morbilliform drug eruption, maculopapular drug eruption, drug rash. EPIDEMIOLOGY. AGE Children < adolescents < adults.
Mar 21, 2024 · Morbilliform exanthematous eruptions. Morbilliform drug eruptions represent the single most common drug reaction, accounting for 50–95% of ASM CADRs (Fig. 1d). Classically, this eruption can begin within 1 to 2 weeks of starting a medication. It can, however, present sooner on re-exposure to medication.
Apr 5, 2024 · Morbiliform rashes are the most common form of drug eruption. Illustrated in Fig. 21-2 is a reaction to chloroquine (Plaquenil). Other common causes are amoxicillin, cephalosporins, semisynthetic penicillins, and barbiturates. Constitutional symptoms of low-grade fever and malaise may be associated with such drug eruptions.
Mar 28, 2024 · Maculopapular or morbilliform reactions commonly caused by. Antibiotics. Anticonvulsants. Allopurinol. NSAIDs. Drug-induced hypersensitivity reaction (also known as drug eruption with eosinophilia and systemic symptoms [DRESS]) is most often caused by. Anticonvulsants. Allopurinol. Sulfonamides
