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  1. Aug 17, 2021 · According to the World Health Organization (WHO), cerebral malaria is defined as a severe form of P. falciparum malaria that causes cerebral manifestations. Typically,...

  2. Cerebral malaria is the most severe neurological complication of infection with Plasmodium falciparum malaria. It is a clinical syndrome characterized by coma and asexual forms of the parasite on peripheral blood smears. Mortality is high and some surviving patients sustain brain injury which manifest as long-term neuro-cognitive impairments.

    • Richard Idro, Kevin Marsh, Kevin Marsh, Chandy C John, Charles R J Newton, Charles R J Newton, Charl...
    • 10.1203/PDR.0b013e3181eee738
    • 2010
    • 2010/10
  3. Feb 9, 2023 · Cerebral malaria. If parasite-filled blood cells block small blood vessels to your brain (cerebral malaria), swelling of your brain or brain damage may occur. Cerebral malaria may cause seizures and coma.

  4. Jul 23, 2020 · Cerebral malaria (CM), results from Plasmodium falciparum infection, and has a high mortality rate. CM survivors can retain life-long post CM sequelae, including seizures and neurocognitive deficits profoundly affecting their quality of life.

    • Nicoline Schiess, Andres Villabona-Rueda, Karissa E. Cottier, Katherine Huether, James Chipeta, Moni...
    • 2020
  5. Feb 2, 2017 · One of the most fretful complications and leading causes of death due to infection with Plasmodium falciparum is cerebral malaria, accounting for around 13% of all malaria-related deaths. 1 It is life threatening especially in children due to their underdeveloped defense mechanism. 2 Malaria itself has a high death toll among communicable diseases.

    • Farah Hafiz Yusuf, Muhammad Yusuf Hafiz, Maria Shoaib, Syed Ahsanuddin Ahmed
    • 2017
  6. Cerebral malaria is the most severe neurological complication of infection with Plasmodium falciparum malaria. It is a clinical syndrome characterized by coma and asexual forms...

  7. Apr 20, 2022 · Cerebral malaria (CM) is characterized by unarousable coma not attributable to other neuro-pathologies combined with Pf parasitemia. Of all severe malaria complications, CM is the most prevalent and deadly, with a mortality rate of 100% if untreated and a patient fatality of 15-25% if treated with current first-line anti-malaria therapy ( 6 ).

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