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CVS COVID-19 Vaccine Near Columbus OH
www.cvs.comPharmacy LocationBy appointment only3307 East Broad Street(614) 235-8605109 South High Street Suite 100(614) 224-4261759 Neil Avenue(614) 224-92751515 West Broad Street(614) 274-16202100 East Dublin Granville Road(614) 891-14101495 West 5th Avenue(614) 486-71592160 North High Street(614) 294-2105Nov 1, 2023 · Doxycycline post-exposure prophylaxis (“DoxyPEP”) is recommended for men who have sex with men and transgender women who have had a sexually transmitted infection (STI) within the past 12 months. You can take it as a single 200 mg dose within 72 hours (3 days) of unprotected sex.
Oct 25, 2022 · Doxycycline is a Food and Drug Administration-approved drug, and providers can prescribe it for uses beyond what it’s been approved for (known as “off label” prescribing).
- Efficacy of doxycycline as PEP to prevent bacterial STIs search strategy:
- References
MEDLINE/PubMed and Embase were searched through June 30, 2023 using the terms: Medline/PubMed: (doxycycline) AND (chlamydia OR gonorrhea OR syphilis) AND (PEP OR post-exposure prophylaxis OR pre-exposure prophylaxis OR PrEP) AND (Clinical Trial[pt]).
EMBASE: (‘doxycycline’/exp OR doxycycline) AND (‘chlamydia’/exp OR chlamydia OR ‘gonorrhea’/exp OR gonorrhea OR ‘syphilis’/exp OR syphilis) AND (pep OR ‘post-exposure prophylaxis’/ex OR ‘post-exposure prophylaxis’ OR ‘pre-exposure prophylaxis’/exp OR ‘pre-exposure prophylaxis’ OR prep) AND randomized. Abstracts presented at major scientific conferences were also reviewed.
Inclusion criteria: randomized controlled trial; English; evaluated PEP as STI bacterial prophylaxis
Exclusion criteria: non-human subjects or in-vitro studies; unrelated papers; duplicates; unavailable full texts; abstract-only papers; case reports; non-English
RCT = randomized controlled trial
MSM = Men who have sex with men
1.Molina JM, Charreau I, Chidiac C, et al. Post-exposure prophylaxis with doxycycline to prevent sexually transmitted infections in men who have sex with men: an open-label randomised substudy of the ANRS IPERGAY trial. Lancet Infect Dis. 2018 Mar;18(3):308-317.
2.Luetkemeyer AF, Donnell D, Dombrowski JC, et al. Postexposure doxycycline to prevent bacterial sexually transmitted infections. N Engl J Med. 2023 Apr 6;388(14):1296-1306. DoxyPEP Reference (Conference Data- needs to be updated when paper available)
3.Jean-Michel Molina, Beatrice Bercot, Lambert Assoumou, Algarte-Genin Michele, Emma Rubenstein, Gilles Pialoux, et al. ANRS 174 DOXYVAC: An Open-Label Randomized Trial to Prevent STIs in MSM on PrEP. CROI [Internet]. 2023 Feb 19;Seattle, Washington. Available from: https://www.croiconference.org/abstract/anrs-174-doxyvac-an-open-label-randomized-trial-to-prevent-stis-in-msm-on-prep/
4.Stewart J, Oware K, Donnell D, Violette L, Odoyo J, Simoni J, et al. Self-reported adherence to event-driven doxycycline postexposure prophylaxis for sexually transmitted infection prevention among cisgender women. STI and HIV 2023 World Congress, Chicago, IL. 2023 Jul 24; Seattle, Washington. Available from: https://www.croiconference.org/abstract/doxycycline-postexposure-prophylaxis-for-prevention-of-stis-among-cisgender-women/.
Mar 9, 2023 · The antibiotic doxycycline seems most effective for preventing chlamydia and syphilis and slightly less effective for preventing gonorrhea. National Institute of Allergy and Infectious Diseases....
- Apoorva Mandavilli
Sep 29, 2023 · Doxycycline Use and Adverse Events. Last Reviewed: September 29, 2023. Source: Division of STD Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention. STD Information from CDC. Facts, Statistics, Treatment, and Other Resources.
DoxyPEP is the first biomedical prevention tool for bacterial STIs that has been shown to be effective and well-tolerated. While it remains an off-label indication, doxycycline is inexpensive and has a history of off-label long-term use for other conditions. National guidance for DoxyPEP is pending.
Dec 18, 2023 · Doxy stands for doxycycline, an antibiotic that we typically use to treat, but also to prevent, infections. PEP stands for post-exposure prophylaxis. The idea behind Doxy-PEP is that an individual will take 200 milligrams of doxycycline, ideally within 24 hours but up to 72 hours, after a sexual exposure to prevent them from acquiring a ...
