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  1. Adults and adolescents doxycycline 100 mg orally 2x/day for 7 days azithromycin 1 gm orally in a single dose OR levofloxacin 500 mg orally 1x/day for 7 days Pregnancy azithromycin 1 gm orally in a single dose amoxicillin 500 mg orally 3x/day for 7 days Infants and children <45 kg4 (nasopharynx, urogenital, and rectal)

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  2. Jul 13, 2023 · Take a single dose of doxycycline as soon as possible but no more than 72 hours after having condomless sex to reduce the risk of three STIs: syphilis, gonorrhea and chlamydia. Doxy-PEP is usually given as two,100-milligram pills or one 200-milligrams tablet.

    • Cervical Diaphragms
    • Multipurpose Prevention Technologies
    • Topical Microbicides and Spermicides
    • NonBarrier Contraception, Female Surgical Sterilization, and Hysterectomy
    • Emergency Contraception
    • Male Circumcision
    • Pre-Exposure Prophylaxis For HIV
    • Pre-Exposure Prophylaxis For STIs
    • Postexposure Prophylaxis For HIV and STIs

    In observational studies, diaphragm use has been demonstrated to protect against cervical gonorrhea, chlamydia, and trichomoniasis (34). However, a trial examining the effect of a diaphragm plus lubricant on HIV acquisition among women in Africa reported no additional protective effect when compared with the use of male condoms alone. Likewise, no ...

    Methods that combine STI and HIV prevention with pregnancy prevention are known as multipurpose prevention technologies (MPTs) (37) (https://www.who.int/ reproductivehealth/topics/linkages/mpts/en). Internal and external condoms are both examples of MPTs because they are effective prevention measures when used correctly for STI and HIV transmission...

    Nonspecific topical microbicides are ineffective for preventing HIV infection (40–45). Tenofovir gel has been studied for prevention of herpes simplex virus 2 (HSV-2) and HIV infections (46,47). Adherence can be low (48), and prevention of HIV infection, especially among women, has not been demonstrated (47,49).Vaginal rings containing dapivirine h...

    Contraceptive methods that are not mechanical barriers offer no protection against HIV or other STIs. The ECHO study observed no differences in HIV incidence rates among women randomly assigned to DMPA, levonorgestrel implant, or copper-containing IUD contraceptive methods (38). A systematic review of epidemiologic evidence reported that the majori...

    Unprotected intercourse exposes women to risks for STIs and unplanned pregnancy. Providers should offer counseling about the option of emergency contraception if pregnancy is not desired. Options for emergency contraception in the United States include copper-containing IUDs and emergency contraceptive pills (ECPs) (58,59). More information is avai...

    Male circumcision reduces the risk for HIV infection and certain STIs among heterosexual men. Three randomized, controlled trials performed in regions of sub-Saharan Africa, where generalized HIV epidemics involving predominantly heterosexual transmission were occurring, demonstrated that male circumcision reduces the risk for HIV acquisition among...

    Daily oral antiretroviral PrEP with a fixed-dose combination of emtricitabine (FTC) and either tenofovir disoproxil fumarate (TDF) or tenofovir alafenamide (TAF) have demonstrated safety (74) and a substantial reduction in the rate of HIV acquisition for MSM (75). TDF/FTC has demonstrated safety and efficacy for mixed-status heterosexual couples (7...

    Providing HSV treatment to persons with HIV and HSV infection has not demonstrated benefit in reducing HIV acquisition among uninfected partners. A large randomized controlled trial evaluated mixed-status heterosexual couples among the partners with HIV infection who also were seropositive for HSV-2 (88). Use of acyclovir had no effect on HIV trans...

    Guidelines for using PEP aimed at preventing HIV and other STIs as a result of sexual exposure are available at https://www.cdc.gov/hiv/pdf/programresources/cdc-hiv-npep-guidelines.pdf. Sexually active persons seeking HIV PEP should be evaluated for PrEP after completing their PEP course and testing negative for HIV. HIV PEP is also discussed elsew...

  3. Doxycycline Use and Adverse Events. Last Reviewed: September 29, 2023. Source: Division of STD Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention. STD Information from CDC. Facts, Statistics, Treatment, and Other Resources.

  4. How Is Doxycycline Used? In previous and current practice, the drug is most often used for the following[1]: “To treat or prevent anthrax (a serious infection that may be spread on purpose as part of a bioterror attack) in people who may have been exposed to anthrax in the air.”

  5. Adults and adolescents: Doxycycline, 100 mg orally twice a day for 7 days Pregnancy and children < 8 years and ≥ 99 lb (45 kg) Azithromycin (Zithromax), 1 g orally in a single dose

  6. Jul 22, 2021 · Gonococcal Infections Among Adolescents and Adults. Gonococcal Infections Among Neonates. Gonococcal Infections Among Infants and Children. Next. Page last reviewed: July 22, 2021. Content source: Division of STD Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention. STI ...

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