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  1. As CDC and others work quickly to evaluate data to inform clinical guidance on the safe and effective use of post-exposure prophylaxis with doxycycline (also called doxy as PEP) to prevent gonorrhea, chlamydia, and syphilis, we acknowledge there are individuals and clinicians who are already engaged in the off-label use of doxycycline as bacterial STI post-exposure prophylaxis or considering it.

  2. Jul 13, 2023 · Take a single dose of doxycycline as soon as possible but no more than 72 hours after having condomless sex to reduce the risk of three STIs: syphilis, gonorrhea and chlamydia. Doxy-PEP is usually given as two,100-milligram pills or one 200-milligrams tablet. Doxycycline should be taken with a glass of water and you should not lie down for 30 ...

  3. Jul 23, 2021 · The term “sexually transmitted infection” (STI) refers to a pathogen that causes infection through sexual contact, whereas the term “sexually transmitted disease” (STD) refers to a recognizable disease state that has developed from an infection. Physicians and other health care providers have a crucial role in preventing and treating STIs.

    • Kimberly A Workowski, Laura H Bachmann, Philip A Chan, Christine M Johnston, Christina A Muzny, Ina ...
    • 2021
  4. Doxycycline is an antibiotic, meaning it “is used to treat a variety of infections caused by certain types of bacteria.”. [1] This type of drug “is in a class of medications called tetracycline antibiotics,” which work “to treat infections by preventing the growth and spread of bacteria.”. [1]

  5. Sexually active adolescents and young adults are at particular risk of chlamydia and gonorrhea infection and other STIs, especially those in vulnerable groups, including young MSM, transgender ...

  6. For chlamydia, doxycycline is the preferred treatment. A test-of-cure is recommended for all cases of pharyngeal gonorrhea and for rectal chlamydia if treated with azithromycin.

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