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Doxycycline hyclate 200mg orally once within 24-72 hours after having condomless anal or oral sex versus no prophylaxis: First STI infection (gonorrhea, chlamydia or syphilis) during a 10-month follow-up period: Reduced risk of acquiring chlamydia and syphilis by 70% (HR 0.30 (95% CI 0.13-0.70) and 73% (HR 0.27 (95% CI 0.07-0.98), respectively.
Jul 23, 2021 · STI PEP in the form of doxycycline 200 mg taken after unprotected anal sex has been studied among MSM and transgender women; results demonstrated reduction in incident chlamydia and syphilis by 70% and 73%, respectively, but no effect on gonorrhea (93).
- Kimberly A Workowski, Laura H Bachmann, Philip A Chan, Christine M Johnston, Christina A Muzny, Ina ...
- 2021
Chlamydia trachomatis (chlamydia).12 Doxycycline is effective against chlamydia and syphilis, is not used for gonorrhea treatment, has an excellent safety profile and low-cost generic formulations,
Oct 11, 2023 · 11 October 2023. Estimated reading time 6 minutes. Africa Studio/Shutterstock.com. On October 2, the US Centers for Disease Control and Prevention (CDC) issued proposed guidelines for using the antibiotic doxycycline as post-exposure prophylaxis to prevent bacterial sexually transmitted infections (STIs), an approach known as doxyPEP.
Apr 6, 2023 · The oral antibiotic doxycycline prevented the acquisition of sexually transmitted infections (STIs) when tested among men who have sex with men (MSM) and transgender women who took the medication within 72 hours of having condomless sex, according to findings published today in the New England Journal of Medicine.
This guideline on the use of doxycycline post-exposure prophylaxis (doxy-PEP) for prevention of bacterial sexually transmitted infections (STIs), including syphilis, chlamydia, and gonorrhea, was developed by the New York State Department of Health AIDS Institute (NYSDOH AI) Clinical Guidelines Program to support clinicians in caring for adults ...
Sep 29, 2023 · Guidelines for the Use of Doxycycline Post-Exposure Prophylaxis for Bacterial STI Prevention. Print. Efficacy of Doxycycline as PEP to Prevent Bacterial STIs. Doxycycline Individual Level Harms – Antimicrobial Resistance. Doxycycline Use and Adverse Events. Last Reviewed: September 29, 2023.
