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  2. Dec 18, 2023 · PEP stands for post-exposure prophylaxis. The idea behind Doxy-PEP is that an individual will take 200 milligrams of doxycycline, ideally within 24 hours but up to 72 hours, after a sexual exposure to prevent them from acquiring a sexually transmitted infection (STI).

  3. Guidelines for the Use of Doxycycline Post-Exposure Prophylaxis for Bacterial STI Prevention. Print. Efficacy of Doxycycline as PEP to Prevent Bacterial STIs. Doxycycline Individual Level Harms – Antimicrobial Resistance. Doxycycline Use and Adverse Events. Last Reviewed: September 29, 2023.

  4. How Is Doxycycline Used? In previous and current practice, the drug is most often used for the following[1]: “To treat or prevent anthrax (a serious infection that may be spread on purpose as part of a bioterror attack) in people who may have been exposed to anthrax in the air.”

  5. Providers who more commonly treat STIs are more likely to prescribe prophylactic doxycycline and believe that benefits outweigh potential for increased antimicrobial resistance. Keywords: Sexually transmitted infections, doxycycline, antimicrobial resistance, providers, bacteria, prophylaxis, United States.

  6. Dec 4, 2023 · Based on its review of the data, the draft guidelines recommend that 200 milligrams of doxycycline within 72 hours of oral, vaginal, or anal sex "should be considered for gay, bisexual, and other MSM, and for TGW, with a history of at least one bacterial STI (i.e., gonorrhea, chlamydia or syphilis) in the last 12 months and who are at ongoing ...

  7. Apr 23, 2024 · Doxycycline is used for bacterial infections, including acne, rosacea, urinary and respiratory tract infections, eye infections, gum disease, gonorrhea, chlamydia, and syphilis. Doxycycline can also be used to prevent malaria and treat infections caused by mites, ticks, or lice.

  8. Apr 6, 2023 · Credit: NIAID. The oral antibiotic doxycycline prevented the acquisition of sexually transmitted infections (STIs) when tested among men who have sex with men (MSM) and transgender women who took the medication within 72 hours of having condomless sex, according to findings published today in the New England Journal of Medicine.