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Dec 1, 2023 · Probably carcinogenic to humans. 95 agents. Group 2B. Possibly carcinogenic to humans. 323 agents. Group 3. Not classifiable as to its carcinogenicity to humans. 500 agents. For definitions of these groups, please see the Preamble.
We are pleased to announce the publication of a list of carcinogenic agents - by cancer site - with sufficient or limited evidence in humans. The list will be updated regularly as new classifications are announced. See List of Classifications by Cancer Site IARC Monographs website.
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- Overview
- The Problem
- Causes
- Risk Factors
- Reducing The Burden
- Prevention
- Early Detection
- Treatment
- Palliative Care
- Who Response
Cancer is a generic term for a large group of diseases that can affect any part of the body. Other terms used are malignant tumours and neoplasms. One definingfeature of cancer is the rapid creation of abnormal cells that grow beyond their usual boundaries, and which can then invade adjoining parts of the body and spread to other organs; the latter...
Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020 (1). The most common in 2020 (in terms of new cases of cancer) were: 1. breast (2.26 million cases); 2. lung (2.21 million cases); 3. colon and rectum (1.93 million cases); 4. prostate (1.41 million cases); 5. skin (non-melanoma) (1.20 million cases); and ...
Cancer arises from the transformation of normal cells into tumour cells in a multi-stage process that generally progresses from a pre-cancerous lesion to a malignant tumour. These changes are the result of the interaction between a person's genetic factorsand three categories of external agents, including: 1. physical carcinogens, such as ultraviol...
Tobacco use, alcohol consumption, unhealthy diet, physical inactivity and air pollution are risk factors for cancer and other noncommunicable diseases. Some chronic infections are risk factors for cancer; this is a particular issue in low- and middle-income countries. Approximately 13% of cancers diagnosed in 2018 globally were attributed to carcin...
Between 30 and 50% of cancers can currently be prevented by avoiding risk factors and implementing existing evidence-based prevention strategies. The cancer burden can also be reduced through early detection of cancer and appropriate treatment and careof patients who develop cancer. Many cancers have a high chance of cure if diagnosed early and tre...
Cancer risk can be reduced by: 1. not using tobacco; 2. maintaining a healthy body weight; 3. eating a healthy diet, including fruit and vegetables; 4. doing physical activity on a regular basis; 5. avoiding or reducing consumption of alcohol; 6. getting vaccinated against HPV and hepatitis B if you belong to a group for which vaccination is recomm...
Cancer mortality is reduced when cases are detected and treated early. There are two components of early detection: early diagnosis and screening.
A correct cancer diagnosis is essential for appropriate and effective treatment because every cancer type requires a specific treatment regimen. Treatment usually includes surgery, radiotherapy, and/or systemic therapy (chemotherapy, hormonal treatments,targeted biological therapies). Proper selection of a treatment regimen takes into consideration...
Palliative care is treatment to relieve, rather than cure, symptoms and suffering caused by cancer and to improve the quality of life of patients and their families. Palliative care can help people live more comfortably. It is particularly neededin places with a high proportion of patients in advanced stages of cancer where there is little chance o...
In 2017, the World Health Assembly passed the Resolution Cancer prevention and control in the context of an integrated approach (WHA70.12) that urgesgovernments and WHO to accelerate action to achieve the targets specified in the Global Action Plan for the prevention and control of NCDs 2013-2020and the 2030 UN Agenda for Sustainable Development to...
organizations to inform risk assessments, formulate decisions about preventive 6 measures, motivate effective cancer control programmes, and choose among 7 options for public health decisions. Monographsevaluations are only one part of 8 the body of information on which decisions to control exposure to carcinogens 9 may be based.
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Volume 100 of the IARC Monographs, A Review of Human Carcinogens, covers all agents previously classified by IARC as "carcinogenic to humans (Group 1)" and was developed by six separate Working Groups: Pharmaceuticals; Biological agents; Arsenic, Metals, Fibres, and Dusts; Radiation; Personal Habits and Indoor Combustions; Chemical Agents and ...
Highlights. The International Agency for Research on Cancer (IARC) classifies potential carcinogens, which can lead to changes in government, industry, and public health policies and practices to support cancer prevention. IARC updated its classification process in 2019 by switching from 5 classification categories to 4, increasing its use of ...