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appropriate MESH terms (pyrexia of unknown origin, fever of unknown origin) in the National Library of Medicine’s computerised search service (PubMed and other related databases). We also consulted Cochrane database systematic reviews. We reviewed all relevant articles as well as the cited references to identify further articles.
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Sep 4, 2023 · Fever, or pyrexia, is the elevation of an individual's core body temperature above a 'set-point' regulated by the body's thermoregulatory center in the hypothalamus. This increase in the body's 'set-point' temperature is often due to a physiological process brought about by infectious causes or non-infectious causes such as inflammation, malignancy, or autoimmune processes. These processes ...
- 2022/09/11
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What does pyrexia mean in medical terms?
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Introduction. The definition of pyrexia of unknown origin (PUO) dates back to 1961; it was described as a persistent fever above 38.3°C (100°F) that evades diagnosis for at least 3 weeks, including 1 week of investigation in hospital. 1 This definition has evolved with faster and more accurate diagnostic techniques and changing models of care, and a week of hospitalisation is no longer ...
- Cristina Fernandez, Nicholas Beeching
- 10.7861/clinmedicine.18-2-170
- 2018
- Clin Med (Lond). 2018 Apr; 18(2): 170-174.
Pyrexia is the medical term for fever, in which the human body temperature rises above the average normal (37 degrees Celsius or 98.6 degrees Fahrenheit). Pyrexia is one of the most common symptoms of numerous medical conditions. There are multiple factors can affect the normal body temperature of an individual.
Sep 16, 2016 · Pyrexia of unknown origin (PUO) is a syndrome that has long tested the skills of physicians to achieve a diagnosis in affected patients. By definition, patients included in this syndrome will be more difficult to diagnose as they have already resisted classification during baseline investigations.
- Robyn W Beresford, Iain B Gosbell, Iain B Gosbell
- 2016
Oct 3, 2016 · The causes of pyrexia are multiple and contribute to different definitions. During infection, fever is usually defined as a temperature greater that 38.3 °C [ 7 , 9 ]; in the post-resuscitation care of cardiac arrest, a threshold of 37.6 °C is used [ 10 ]; and in stroke, thresholds of 37.2, 37.5 and 38 °C are all applied [ 11 ].
Sep 28, 2021 · Pyrexia or fever of unknown origin is defined as prolonged fever in an immunocompetent patient that has an unknown cause despite standard investigations. Infections, non-infectious inflammatory diseases, malignancy and other diseases can all cause pyrexia of unknown origin. The diagnostic work-up is based on the identification of potential diagnostic clues, and further investigation is based ...
