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  1. Dec 21, 2021 · 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is known to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in humans, both epidemiological and on the mechanism of carcinogenesis. TCDD was first listed in the Second Annual Report on Carcinogens as reasonably anticipated to be a human carcinogen. Subsequently, a number of studies were published that examined cancer ...

  2. In 1999, the International Agency for Research on Cancer (IARC) classified one of the dioxin congeners (TCDD or 2,3,7,8-tetrachlorodibenzo-p-dioxin) as a human carcinogen.

  3. Dec 1, 2023 · Note: In September 2022, four additional individual Group 1 agents were created by splitting up some existing agent groupings because not all agents in the groups had the same cancer sites with sufficient and limited evidence for cancer in humans. Three strains of human papillomavirus (HPV) were split from a larger grouping of HPV strains.

  4. IARC group 1 Carcinogens are substances, chemical mixtures, and exposure circumstances which have been classified as carcinogenic to humans by the International Agency for Research on Cancer (IARC). [1] This category is used when there is sufficient evidence of carcinogenicity in humans. Exceptionally, an agent ( chemical mixture) may be placed ...

  5. Jul 1, 2011 · Abstract. The authors reviewed the epidemiologic studies on exposure to 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) and cancer risk, published since the last full-scale review made by the International Agency for Research on Cancer Monographs program in 1997. The update of a cohort of US herbicide producers generated negative results overall ...

  6. Nov 29, 2016 · IARC monographs on the evaluation of carcinogenic risks to humans/World Health Organization, International Agency for Research on Cancer 69, 1–631 (1997). Chemical agents and related occupations.

  7. Nov 14, 2023 · IARC Monographs evaluate the carcinogenicity of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS). The International Agency for Research on Cancer (IARC), the cancer agency of the World Health Organization (WHO), has evaluated the carcinogenicity of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS).

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