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  2. May 3, 2024 · Healthcare associated infections are caused by pathogens that are often resistant to drugs and can rapidly lead to deteriorating clinical conditions. Antimicrobial resistance is a major factor determining clinical unresponsiveness to treatment and rapid evolution to sepsis and septic shock.

  3. 3 days ago · Sepsis, systemic inflammatory condition that occurs as a complication of infection and in severe cases may be associated with acute and life-threatening organ dysfunction. Sepsis is a common cause of illness and mortality in hospitals. Learn more about the causes, symptoms, and treatment of sepsis.

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  4. en.wikipedia.org › wiki › SepsisSepsis - Wikipedia

    May 4, 2024 · Microbial factors. Bacterial virulence factors, such as glycocalyx and various adhesins, allow colonization, immune evasion, and establishment of disease in the host. Sepsis caused by gram-negative bacteria is thought to be largely due to a response by the host to the lipid A component of lipopolysaccharide, also called endotoxin.

    • May be rapid (less than three hours) or prolonged (several days)
  5. Apr 23, 2024 · Sepsis is a life-threatening condition that occurs when the body's response to an infection causes widespread inflammation. It is a serious medical emergency that requires immediate attention. Sepsis can affect people of all ages, but it is more common in older adults and those with weakened immune systems.

  6. 6 days ago · Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Evidence of organ dysfunction includes clinical and laboratory abnormalities of the respiratory system, coagulation, liver, cardiovascular system, nervous system, and kidneys ( Table 79–1 ).

  7. 3 days ago · DEFINITIONS. Sepsis: a life-threatening organ dysfunction caused by a dysregulated host response to infection. Septic shock: a subset of sepsis in which underlying circulatory and cellular/metabolic abnormalities lead to substantially increased mortality risk.

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