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  1. Mar 21, 2019 · Sepsis is a medical emergency that describes the body’s systemic immunological response to an infectious process that can lead to end-stage organ dysfunction and death.

  2. Sep 9, 2018 · Sepsis is a medical emergency that describes the bodys sys-temic immunological response to an infectious process that can lead to end-stage organ dysfunction and death.

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  4. The true incidence of sepsis in any given country is unknown. The reported incidence is dependent on the specific definition used, the infecting organism, the reporting mechanism (such as the use of the International Classification of Diseases-9 coding systems) and the requirement for either organ support or intensive care.

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  5. Although the clinical definition of microbial sepsis is still controversial, definition can be derived from its well-known clinical picture [4, 11, 16] and from the underlying pathophysiological processes which form the biological background of what is con sidered the septic picture.

  6. Sepsis develops in 750,000 people annually, and more than 210,000 of them die. 1,2 After numerous unsuccessful trials of antiinflammatory agents in patients with sepsis, investigators doubted that mortality could be decreased. Advances in unraveling the pathophysiolo-gy and genetic basis for the host response to sepsis have changed the ...

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