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  1. Feb 13, 2024 · A sepsis definition should describe what sepsis “is.” 4 In contrast, the syndrome cannot presently be diagnosed using any standardized, validated test and hence sepsis definitions cannot readily be applied to the clinical setting. Consequently, there is a need to establish objective parameters that can be measured in individual animals, and ...

  2. Mar 21, 2019 · Abstract. There has been a significant evolution in the definition and management of sepsis over the last three decades. This is driven in part due to the advances made in our understanding of its pathophysiology. There is evidence to show that the manifestations of sepsis can no longer be attributed only to the infectious agent and the immune ...

    • Bishal Gyawali, Karan Ramakrishna, Amit S Dhamoon
    • 2019
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  4. Feb 13, 2024 · International, multicenter position statement on the need for consensus definitions of sepsis in veterinary medicine. Setting. Veterinary private practice and university teaching hospitals. Animals. Dogs and cats. Interventions. None. Measurements and Main Results. Sepsis is a life-threatening condition associated with the body's response to an ...

  5. Animals: Dogs and cats. Interventions: None. Measurements and main results: Sepsis is a life-threatening condition associated with the body's response to an infection. In human medicine, sepsis has been defined by consensus on 3 occasions, most recently in 2016. In veterinary medicine, there is little uniformity in how sepsis is defined and no ...

  6. Sepsis is a serious life-threatening illness caused by a myriad of different infectious etiologies, host responses, and clinical contexts [1]. It is a prevailing cause of mortality in small animal patients, with a recent multicenter study showing a mortality rate of 70% in septic dogs that developed multiorgan dysfunction [2]. Understanding of the pathophysiology, diagnostic criteria, and ...

    • Thandeka R. Ngwenyama
    • 2021
  7. the driving pathological process in sepsis because it is now known that sepsis involves activation of both pro- and anti-inflammatory responses91 and is accompanied by dysfunction in the cardiovas-cular, neuronal, autonomic, hormonal, bioenergetic, metabolic, and coagulation systems.92,93 Per the Sepsis-3 consensus, sepsis is the

  8. Sep 9, 2018 · Definition. Over the years, our understanding of the complex patho-physiology of sepsis has improved, and so has our ability to define sepsis. The word sepsis is derived from the Greek word for “decomposition” or “decay,” and its first docu-mented use was about 2700 years ago in Homer’s poems. It.

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