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  1. the driving pathological process in sepsis because it is now known that sepsis involves activation of both pro- and anti-inflammatory responses91 and is accompanied by dysfunction in the cardiovas-cular, neuronal, autonomic, hormonal, bioenergetic, metabolic, and coagulation systems.92,93 Per the Sepsis-3 consensus, sepsis is the

  2. Feb 13, 2024 · International, multicenter position statement on the need for consensus definitions of sepsis in veterinary medicine. Setting. Veterinary private practice and university teaching hospitals. Animals. Dogs and cats. Interventions. None. Measurements and Main Results. Sepsis is a life-threatening condition associated with the body's response to an ...

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  4. Animals: Dogs and cats. Interventions: None. Measurements and main results: Sepsis is a life-threatening condition associated with the body's response to an infection. In human medicine, sepsis has been defined by consensus on 3 occasions, most recently in 2016. In veterinary medicine, there is little uniformity in how sepsis is defined and no ...

  5. Feb 13, 2024 · A sepsis definition should describe what sepsis “is.” 4 In contrast, the syndrome cannot presently be diagnosed using any standardized, validated test and hence sepsis definitions cannot readily be applied to the clinical setting. Consequently, there is a need to establish objective parameters that can be measured in individual animals, and ...

  6. Sep 9, 2018 · Definition. Over the years, our understanding of the complex patho-physiology of sepsis has improved, and so has our ability to define sepsis. The word sepsis is derived from the Greek word for “decomposition” or “decay,” and its first docu-mented use was about 2700 years ago in Homer’s poems. It.

  7. Sepsis is a serious life-threatening illness caused by a myriad of different infectious etiologies, host responses, and clinical contexts [1]. It is a prevailing cause of mortality in small animal patients, with a recent multicenter study showing a mortality rate of 70% in septic dogs that developed multiorgan dysfunction [2]. Understanding of the pathophysiology, diagnostic criteria, and ...

  8. Mar 22, 2019 · Despite the new definitions of sepsis, the proposals to improve the animal models , the progresses made in understanding the pathophysiology of sepsis, the advances in technology, and the trends ...