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  1. Feb 13, 2024 · A sepsis definition should describe what sepsis “is.” 4 In contrast, the syndrome cannot presently be diagnosed using any standardized, validated test and hence sepsis definitions cannot readily be applied to the clinical setting. Consequently, there is a need to establish objective parameters that can be measured in individual animals, and ...

  2. Animals: Dogs and cats. Interventions: None. Measurements and main results: Sepsis is a life-threatening condition associated with the body's response to an infection. In human medicine, sepsis has been defined by consensus on 3 occasions, most recently in 2016. In veterinary medicine, there is little uniformity in how sepsis is defined and no ...

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  4. Mar 21, 2019 · Abstract. There has been a significant evolution in the definition and management of sepsis over the last three decades. This is driven in part due to the advances made in our understanding of its pathophysiology. There is evidence to show that the manifestations of sepsis can no longer be attributed only to the infectious agent and the immune ...

    • Bishal Gyawali, Karan Ramakrishna, Amit S Dhamoon
    • 2019
  5. Feb 13, 2024 · Sepsis is a life-threatening condition associated with the body's response to an infection. In human medicine, sepsis has been defined by consensus on 3 occasions, most recently in 2016. In veterinary medicine, there is little uniformity in how sepsis is defined and no consensus on how to identify it clinically.

  6. Dec 24, 2022 · Sepsis is an illness in which the body has a severe response to bacteria or other germs. The body may develop this inflammatory response by the immune system to microbes in the blood, urine, lungs, skin, or other tissues. A popular term for sepsis is blood poisoning. Severe sepsis is the systemic inflammatory response, infection, and the ...

  7. Sepsis is a serious life-threatening illness caused by a myriad of different infectious etiologies, host responses, and clinical contexts [1]. It is a prevailing cause of mortality in small animal patients, with a recent multicenter study showing a mortality rate of 70% in septic dogs that developed multiorgan dysfunction [2]. Understanding of the pathophysiology, diagnostic criteria, and ...

  8. Oct 10, 2007 · Sepsis encompasses a spectrum of illness that ranges from minor signs and symptoms through to organ dysfunction and shock. Sepsis ranks in the top 10 causes of death. The pathophysiology of sepsis arises largely from the response of the host's innate immune system, under the influence of genetic factors.