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      • In sepsis, blood pressure drops, resulting in septic shock. Major organs and body systems, including the kidneys, liver, lungs, and central nervous system, stop working properly because of poor blood flow. Most cases of septic shock are caused by Gram-positive bacteria, followed by endotoxin-producing Gram-negative bacteria.
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  2. Feb 13, 2024 · This review is intended to serve as the foundation of current efforts to establish a consensus definition for sepsis in small animals and ultimately generate evidence-based criteria for its recognition in veterinary clinical practice.

  3. Animals: Dogs and cats. Interventions: None. Measurements and main results: Sepsis is a life-threatening condition associated with the body's response to an infection. In human medicine, sepsis has been defined by consensus on 3 occasions, most recently in 2016.

  4. Mar 22, 2019 · Despite the new definitions of sepsis, the proposals to improve the animal models , the progresses made in understanding the pathophysiology of sepsis, the advances in technology, and the trends ...

    • Jean-Marc Cavaillon, Fabrice Chrétien, Fabrice Chrétien
    • 2019
  5. Feb 13, 2024 · Animals. Dogs and cats. Interventions. None. Measurements and Main Results. Sepsis is a life-threatening condition associated with the body's response to an infection. In human medicine, sepsis has been defined by consensus on 3 occasions, most recently in 2016.

  6. Mar 21, 2019 · Abstract. There has been a significant evolution in the definition and management of sepsis over the last three decades. This is driven in part due to the advances made in our understanding of its pathophysiology. There is evidence to show that the manifestations of sepsis can no longer be attributed only to the infectious agent and the immune ...

    • Bishal Gyawali, Karan Ramakrishna, Amit S Dhamoon
    • 2019
  7. May 21, 2023 · Bacterial sepsis is a life-threatening condition that arises when the body's response to an infection injures its tissues and organs. Sepsis is caused by conditions that threaten the functional integrity of the host, such as microbial invasion.

  8. Mar 4, 2021 · In 2017, the international Surviving Sepsis Campaign (iSSC) published revised guidelines for the diagnosis and treatment of sepsis and septic shock after publication of the Sepsis-3 definition in 2016, a renewed definition of sepsis as life-threatening organ dysfunction caused by a dysregulated host response to an infection [3, 4].

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