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  2. May 9, 2023 · Pediatric definitions remain despite the new 2016 adult definitions and criteria (Sepsis-3), where “sepsis” is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection and “septic shock” is a subset of sepsis with circulatory and cellular/metabolic dysfunction associated with a higher risk of ...

  3. May 25, 2022 · Consistent with the IPSCC definitions, abnormal vital signs, laboratory evidence of inflammation, and microbiological confirmation were the criteria most commonly used for the diagnosis of children with sepsis ( Fig 3A, and Supplemental Table 9 ).

    • Morin, Luc
  4. Pediatric Sepsis. Key Points: . Sepsis is an overwhelming and life-threatening response to an infection that can cause dysfunction of multiple organ systems. In pediatrics, diagnosing sepsis is especially challenging as children can compensate for severe illness for prolonged periods.

  5. While sepsis is a serious condition at any age, it is particularly dangerous for children because their symptoms can be more difficult to detect. “The biggest difference between adult and pediatric sepsis is recognition,” says Yale Medicine pediatric intensive care doctor Sarah Kandil, MD. “A lot of symptoms we look for in sepsis, like a ...

  6. Jun 11, 2020 · The goals of this systematic review are to synthesize evidence on individual factors, clinical criteria, and/or illness severity scores for the recognition of possible sepsis, sepsis, septicemia, and septic shock in children with suspected or documented infections and to synthesize evidence on factors, criteria, and scores that may be used to ...

    • Kusum Menon, Luregn J Schlapbach, Luregn J Schlapbach, Samuel Akech, Andrew Argent, Kathleen Chiotos...
    • 10.1097/CCE.0000000000000123
    • 2020
    • Crit Care Explor. 2020 Jun; 2(6): e0123.
  7. Jul 19, 2023 · Sepsis is a significant cause of maternal, neonatal and child mortality. Consequently, combating sepsis will contribute to achievement of Sustainable Development Goals (SDGs) targets 3.8 on quality of care, and 3.1 and 3.2 by improving mortality rates in these vulnerable populations. Sepsis can also ultimately lead to death in patients affected ...

  8. May 9, 2023 · Pediatric sepsis remains an important cause of morbidity and mortality in children. This review will summarize the main aspects of the definition, the current evidence base for interventions discuss some controversial themes and point towards possible areas of improvement.

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