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      • Pediatric sepsis is generally considered to comprise a spectrum of disorders that result from infection by bacteria, viruses, fungi, or parasites or the toxic products of these microorganisms.
      emedicine.medscape.com › article › 972559-overview
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  2. May 9, 2023 · Pediatric definitions remain despite the new 2016 adult definitions and criteria (Sepsis-3), where “sepsis” is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection and “septic shock” is a subset of sepsis with circulatory and cellular/metabolic dysfunction associated with a higher risk of ...

  3. While sepsis is a serious condition at any age, it is particularly dangerous for children because their symptoms can be more difficult to detect. “The biggest difference between adult and pediatric sepsis is recognition,” says Yale Medicine pediatric intensive care doctor Sarah Kandil, MD. “A lot of symptoms we look for in sepsis, like a ...

  4. Specifically, the Third International Consensus Definitions for Sepsis and Septic Shock (Balamuth 2022) stresses that sepsis is a function of 4 variables, namely: threat to life. organ dysfunction (using pSOFA score) dysregulated host response. presence of highly suspected or documented infection.

  5. May 25, 2022 · Consistent with the IPSCC definitions, abnormal vital signs, laboratory evidence of inflammation, and microbiological confirmation were the criteria most commonly used for the diagnosis of children with sepsis ( Fig 3A, and Supplemental Table 9 ).

    • Morin, Luc
  6. Jun 11, 2020 · The goals of this systematic review are to synthesize evidence on individual factors, clinical criteria, and/or illness severity scores for the recognition of possible sepsis, sepsis, septicemia, and septic shock in children with suspected or documented infections and to synthesize evidence on factors, criteria, and scores that may be used to ...

    • Kusum Menon, Luregn J Schlapbach, Luregn J Schlapbach, Samuel Akech, Andrew Argent, Kathleen Chiotos...
    • 10.1097/CCE.0000000000000123
    • 2020
    • Crit Care Explor. 2020 Jun; 2(6): e0123.
  7. May 3, 2024 · Sepsis is a serious condition that happens when the body’s immune system has an extreme response to an infection. The body’s reaction causes damage to its own tissues and organs. Sepsis can affect anyone, but people who are older, very young, pregnant or have other health problems are at higher risk.

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