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  1. May 9, 2023 · Sepsis causes hypovolemia due to capillary leak, vasodilation and fluid loss to the third space. Evidence of inadequate oxygen delivery and tissue perfusion (skin, brain, and kidneys) often accompanies sepsis in children. However, early identification of sepsis in children can be very difficult as the early symptoms may be very non-specific.

  2. While sepsis is a serious condition at any age, it is particularly dangerous for children because their symptoms can be more difficult to detect. “The biggest difference between adult and pediatric sepsis is recognition,” says Yale Medicine pediatric intensive care doctor Sarah Kandil, MD. “A lot of symptoms we look for in sepsis, like a ...

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  4. May 9, 2023 · Purpose of Review Pediatric sepsis remains an important cause of morbidity and mortality in children. This review will summarize the main aspects of the definition, the current evidence base for interventions discuss some controversial themes and point towards possible areas of improvement. Recent Findings Controversy remains regarding the accurate definition, resuscitation fluid volume and ...

  5. May 25, 2022 · BACKGROUND AND OBJECTIVES. Definitions for pediatric sepsis were established in 2005 without data-driven criteria. It is unknown whether the more recent adult Sepsis-3 definitions meet the needs of providers caring for children. We aimed to explore the use and applicability of criteria to diagnose sepsis and septic shock in children across the world.METHODS. This is an international electronic ...

  6. May 3, 2024 · Sepsis is a serious condition that happens when the body’s immune system has an extreme response to an infection. The body’s reaction causes damage to its own tissues and organs. Sepsis can affect anyone, but people who are older, very young, pregnant or have other health problems are at higher risk.

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