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  2. May 9, 2023 · Pediatric sepsis remains an important cause of morbidity and mortality in children. This review will summarize the main aspects of the definition, the current evidence base for interventions discuss some controversial themes and point towards possible areas of improvement.

  3. This clinical pathway was developed by a consensus group of Johns Hopkins All Childrens Hospital (JHACH) physicians, advanced practice providers, nurses and pharmacists to standardize the recognition and management of children presenting with clinical signs of sepsis.

  4. May 25, 2022 · Consistent with the IPSCC definitions, abnormal vital signs, laboratory evidence of inflammation, and microbiological confirmation were the criteria most commonly used for the diagnosis of children with sepsis ( Fig 3A, and Supplemental Table 9 ).

    • Morin, Luc
  5. Nov 23, 2021 · ‘Sepsis’ was defined as life-threatening organ dysfunction caused by a dysregulated host response to infection; and ‘septic shock’ was defined as the subset of sepsis with circulatory and cellular/metabolic dysfunction associated with a higher risk of mortality 4 (see Table 2 for ‘adult’ definitions of sepsis). Table 2.

  6. May 3, 2024 · Sepsis is usually caused by bacterial infections but may be the result of other infections such as viruses, parasites or fungi. Its treatment requires medical care, including the use of antimicrobials, intravenous fluids and other measures.

  7. Dec 15, 2023 · Sepsis in children may present initially with non-specific, non-localised symptoms (especially in younger age groups). Therefore it is important to have a low threshold for suspecting sepsis as the initial clinical presentation of sepsis.

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