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1. www.ccjm.org › content › ccjomSepsis and septic shock: Guideline-based management

   www.ccjm.org › content › ccjom

   S epsis and particularly septic shock should be recognized as medical emergen-cies in which time matters, as in stroke and acute myocardial infarction. Early recognition and rapid institution of resuscitative measures are critical. But recognizing sepsis can be a challenge, and best management practices continue to evolve.

   • File Size: 181KB
   • Author: Siddharth Dugar, Chirag Choudhary, Abhijit Duggal

   • Page Count: 12
   • Publish Year: 2020

2. www.nursingcenter.com › getattachment › ClinicalManagement of Sepsis and Septic Shock in Adults

   www.nursingcenter.com › getattachment › Clinical

   septic shock recognition, for patients with a high likelihood of sepsis or possible septic shock. • For patients with possible sepsis but without shock, rapid assessment of an infectious versus non-infectious cause of acute illness is recommended (within 3 hours, when possible). o This includes: History Clinical examination

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4. www.cdc.gov › sepsis › pdfsLife After Sepsis Fact Sheet. - Centers for Disease Control ...

   www.cdc.gov › sepsis › pdfs

   LIFE AFTER SEPSIS FACT SHEET. It is also not unusual to have the following feelings once you’re at home: • Unsure of yourself. • Not caring about your appearance. • Wanting to be alone, avoiding friends and family. • Flashbacks, bad memories. • Confusing reality (e.g., not sure what is real and what isn’t)

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5. www.uptodate.com › contents › evaluation-andEvaluation and management of suspected sepsis and septic ...

   www.uptodate.com › contents › evaluation-and

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   Feb 13, 2024 · Sepsis is a clinical syndrome characterized by a dysregulated host response to infection. There is a continuum of severity ranging from sepsis to septic shock. Although wide-ranging and dependent upon the population studied, mortality has been estimated to be ≥10 percent and ≥40 percent when shock is present [ 1,2 ].

6. www.sccm.org › SurvivingSepsisCampaign › GuidelinesSSC Adult Patients | SCCM

   www.sccm.org › SurvivingSepsisCampaign › Guidelines

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   Minimizing the time to treatment acknowledges the urgency that exists for patients with sepsis and septic shock. * Note that the description of the hour-1 bundle above is the most current description, having passed all approval points effective October 10, 2019.

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   How important is timely treatment for sepsis and septic shock?

   • The importance of timely treatment, particularly with antibiotics, was illustrated in a database study of nearly 50,000 patients with sepsis and septic shock who were treated with various types of protocolized treatment bundles (that included fluids and antibiotics, blood cultures, and serum lactate measurements) [ 31 ].

   Evaluation and management of suspected sepsis and septic shock in

   www.uptodate.com/contents/evaluation-and-management-of-suspected-sepsis-and-septic-shock-in-adults/print

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   When should antibiotic therapy be initiated for sepsis & septic shock?

   • Timing — Once a presumed diagnosis of sepsis or septic shock has been made, optimal doses of appropriate intravenous antibiotic therapy should be initiated, preferably within one hour of presentation and after cultures have been obtained (see 'Initial investigations' above).

   Evaluation and management of suspected sepsis and septic shock in

   www.uptodate.com/contents/evaluation-and-management-of-suspected-sepsis-and-septic-shock-in-adults/print

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   When should a sepsis & septic shock bundle be used?

   • For critically ill patients with sepsis or septic shock, time is of the essence. Although the starting time for the Hour-1 bundle is recognition of sepsis, both sepsis and septic shock should be viewed as medical emergencies requiring rapid diagnosis and immediate intervention.

   SSC Adult Patients | SCCM

   www.sccm.org/SurvivingSepsisCampaign/Guidelines/Adult-Patients

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8. www.ncbi.nlm.nih.gov › books › NBK430939Septic Shock - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK430939

   Jun 12, 2023 · Septic shock, the most severe complication of sepsis, carries a high mortality. Septic shock occurs in response to an inciting agent, which causes both pro-inflammatory and anti-inflammatory immune system activation. This occurs in concert with the activation of monocytes, macrophages, and neutrophils that interact with the endothelium through ...

9. www.ncbi.nlm.nih.gov › pmc › articles2023 Update on Sepsis and Septic Shock in Adult Patients ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Apr 28, 2023 · Vasopressin (VP) may be considered a second-line choice for septic shock treatment . According to the SSC’s recommendations, it can be administered (at a dose of 0.25–0.5 μg/kg/min) in addition to NE to obtain the target MAP by decreasing the dosage of the latter and reducing the side effects due to adrenergic overload . Furthermore, two ...