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  2. www.ncbi.nlm.nih.gov › pmc › articlesStreptomyces from traditional medicine: sources of new...

    Jul 21, 2020 · Antibiotics from Streptomyces. The antibiotic streptomycin was discovered in 1943 by Albert Schatz, a PhD student of Selman Waksman, with help from others including Doris Ralston, Elizabeth Bugie and Christine Reilly [ 9 ].

    • Table 2

      Given the increased reporting of multi-resistant bacteria...

  3. www.ncbi.nlm.nih.gov › books › NBK555886Streptomycin - StatPearls - NCBI Bookshelf

    Jul 4, 2023 · HHS. USA.gov. Streptomycin is the first discovered aminoglycoside antibiotic, originally isolated from the bacteria Streptomyces griseus. It is now primarily used as part of the multi-drug treatment of pulmonary tuberculosis. It has additional activity against several aerobic gram-negative bacteria.

    • Mitchell Waters, Prasanna Tadi
    • 2023/07/04

  4. www.nature.com › articles › ja201762A brief history of antibiotics and select advances in their ...

    Jul 5, 2017 · Another important milestone in the history of antibiotics was the discovery of streptomycin (6, Figure 1) from Actinomyces griseus (now Streptomyces griseus), the first aminoglycoside antibiotic...

    • Kyriacos C Nicolaou, Stephan Rigol
    • 2018

  5. www.ncbi.nlm.nih.gov › pmc › articlesMethicillin-resistant Staphylococcus aureus emerged long ...

    Jul 20, 2017 · Discovered in the early 1940s, streptomycin was demonstrated to have activity against Gram-positive pathogens, and was used in the UK in 1947 during the first ever randomized clinical trials studying the efficacy of streptomycin in the treatment of pulmonary tuberculosis [28, 29].

    • Catriona P. Harkins, Catriona P. Harkins, Bruno Pichon, Michel Doumith, Julian Parkhill, Henrik West...
    • 10.1186/s13059-017-1252-9
    • 2017
    • Genome Biol. 2017; 18: 130.

  6. en.wikipedia.org › wiki › StreptomycinStreptomycin - Wikipedia

    Streptomycin was first isolated on October 19, 1943, by Albert Schatz, a PhD student in the laboratory of Selman Abraham Waksman at Rutgers University in a research project funded by Merck and Co. Waksman and his laboratory staff discovered several antibiotics, including actinomycin, clavacin, streptothricin, streptomycin, grisein, neomycin ...

    • 84% to 88% IM (est.) 0% by mouth
    • Kidney
    • C₂₁H₃₉N₇O₁₂

  7. www.sciencelearn.org.nz › interactive_timeline › 15Antibiotics and antimicrobial resistance – a timeline

    Jul 20, 2023 · 1943 – Streptomycin discovered. Streptomycin is the first antibiotic to be successful against tuberculosis. 1944 – Golden age of antibiotics. The discovery of natural product antibiotics peaks in the mid-1950s – including streptomycin, cephalosporins, tetracyclines, vancomycin and methicillin.

  8. www.britannica.com › science › streptomycinStreptomycin | Antibiotic, Bacterial Resistance & Tuberculosis

    Streptomycin was discovered by American biochemists Selman Waksman, Albert Schatz, and Elizabeth Bugie in 1943. The drug acts by interfering with the ability of a microorganism to synthesize certain vital proteins. It was the first antimicrobial agent developed after penicillin and the first antibiotic effective in treating tuberculosis.

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