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When was streptomycin first used?
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History. Streptomycin was first isolated on October 19, 1943, by Albert Schatz, a PhD student in the laboratory of Selman Abraham Waksman at Rutgers University in a research project funded by Merck and Co. Waksman and his laboratory staff discovered several antibiotics, including actinomycin, clavacin, streptothricin, streptomycin, grisein ...
- 84% to 88% IM (est.) 0% by mouth
- Kidney
- C₂₁H₃₉N₇O₁₂
For decades, hundreds of thousands of cases had been reported every year, but by 1953, only 84,000 new cases of tuberculosis were reported in the United States. The death rates associated with the disease also dropped off precipitously: while in 1930, 70 out of every 100,000 people in the United States died from the disease, by 1954 only 10 out ...
Jul 21, 2020 · The antibiotic streptomycin was discovered in 1943 by Albert Schatz, a PhD student of Selman Waksman, with help from others including Doris Ralston, Elizabeth Bugie and Christine Reilly [ 9 ].
- Gerry A. Quinn, Aiya M. Banat, Alyaa M. Abdelhameed, Ibrahim M. Banat
- 10.1099/jmm.0.001232
- 2020
- J Med Microbiol. 2020 Aug; 69(8): 1040-1048.
Apr 27, 2022 · Streptomycin has been referred to as the “wonder drug” due to the transformative effect it had on the prognosis of patients suffering from tuberculosis when it was first discovered. It spurred the discovery and invention of antibiotic drugs within the category know as aminoglycosides.
Streptomycin was discovered by American biochemists Selman Waksman, Albert Schatz, and Elizabeth Bugie in 1943. The drug acts by interfering with the ability of a microorganism to synthesize certain vital proteins. It was the first antimicrobial agent developed after penicillin and the first antibiotic effective in treating tuberculosis.
Jul 4, 2023 · HHS. USA.gov. Streptomycin is the first discovered aminoglycoside antibiotic, originally isolated from the bacteria Streptomyces griseus. It is now primarily used as part of the multi-drug treatment of pulmonary tuberculosis. It has additional activity against several aerobic gram-negative bacteria.
- Mitchell Waters, Prasanna Tadi
- 2023/07/04
Jul 5, 2017 · Another important milestone in the history of antibiotics was the discovery of streptomycin (6, Figure 1) from Actinomyces griseus (now Streptomyces griseus), the first aminoglycoside...
