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Streptomycin was first isolated on October 19, 1943, by Albert Schatz, a PhD student in the laboratory of Selman Abraham Waksman at Rutgers University in a research project funded by Merck and Co. Waksman and his laboratory staff discovered several antibiotics, including actinomycin, clavacin, streptothricin, streptomycin, grisein, neomycin ...
- 84% to 88% IM (est.) 0% by mouth
- Kidney
- C₂₁H₃₉N₇O₁₂
For decades, hundreds of thousands of cases had been reported every year, but by 1953, only 84,000 new cases of tuberculosis were reported in the United States. The death rates associated with the disease also dropped off precipitously: while in 1930, 70 out of every 100,000 people in the United States died from the disease, by 1954 only 10 out ...
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Jul 4, 2023 · HHS. USA.gov. Streptomycin is the first discovered aminoglycoside antibiotic, originally isolated from the bacteria Streptomyces griseus. It is now primarily used as part of the multi-drug treatment of pulmonary tuberculosis. It has additional activity against several aerobic gram-negative bacteria.
- Mitchell Waters, Prasanna Tadi
- 2023/07/04
Jul 20, 2023 · 1943 – Streptomycin discovered. Streptomycin is the first antibiotic to be successful against tuberculosis. 1944 – Golden age of antibiotics. The discovery of natural product antibiotics peaks in the mid-1950s – including streptomycin, cephalosporins, tetracyclines, vancomycin and methicillin.
Jul 21, 2020 · The antibiotic streptomycin was discovered in 1943 by Albert Schatz, a PhD student of Selman Waksman, with help from others including Doris Ralston, Elizabeth Bugie and Christine Reilly [ 9 ].
- Gerry A. Quinn, Aiya M. Banat, Alyaa M. Abdelhameed, Ibrahim M. Banat
- 10.1099/jmm.0.001232
- 2020
- J Med Microbiol. 2020 Aug; 69(8): 1040-1048.
Streptomycin was discovered by American biochemists Selman Waksman, Albert Schatz, and Elizabeth Bugie in 1943. The drug acts by interfering with the ability of a microorganism to synthesize certain vital proteins.
Various aminoglycosides have been introduced into clinical practice since Waksman's discovery of streptomycin more than 40 years ago. The aminoglycosides available for current clinical use in the United States are streptomycin, kanamycin, neomycin, gentamicin, tobramycin, amikacin, and netilmicin; dibekacin and sisomicin (the latter derived from netilmicin) are marketed worldwide but not ...
