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Clarithromycin (brand name: Biaxin®) is a macrolide antibiotic used to treat certain bacterial infections, such as Helicobacter spp and Rhodocuccus equi in foals. Its use in cats, dogs, ferrets, horses, to treat bacterial infections is ‘off label’ or ‘extra label’.
Dose of Clarithromycin (Biaxin) in Dogs and Cats. Dogs: 4–12 mg/kg i.v. infusion, p.o. q12h. Doses of 15–25 mg/kg p.o. total daily dose divided q8–12h is recommended in the treatment of leproid granuloma syndrome combined with rifampin 10–15 mg/kg p.o. q24h.
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H pylori infections in people are treated with double or triple antimicrobial agent therapy plus an acid secretory inhibitor (eg, clarithromycin, amoxicillin, bismuth, and ranitidine) for 2 weeks, and similar therapeutic approaches have been used in veterinary medicine.
Find custom compounded clarithromycin medication for animals and articles with clarithromycin information from Wedgewood Pharmacy, a leading veterinary pharmacy.
Clarithromycin and azithromycin have similar bioavailability in foals—56% and 57%, respectively. Erythromycin is labeled for administration IM in dogs and cats, PO in chickens and turkeys, and intramammary use in cattle.
On the veterinary diagnosis and treatment of your choice of species: dogs, cats, rabbits, exotics, horses and cattle. View Clarithromycin & more Canis resources at Vetlexicon. Over 28,000 peer-reviewed resources: Bovis, Equis, Felis, Lapis & Exotis.
Coadministration of gamithromycin and rifampin in foals leads to increased plasma exposure to gamithromycin due to rifampin's inhibition of hepatic elimination mechanisms. Coadministration of rifampin and clarithromycin decreases clarithromycin's bioavailability by up to 90%.
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