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  1. Located in the Greater Los Angeles region of Southern California, the city's population was 310,227 at the 2020 census, making Santa Ana the second most populous city in Orange County (after Anaheim), the 13th-most populous city in California, and the 64th densest large city in the United States.

  2. Located in the Greater Los Angeles region of Southern California, the city's population was 310,227 at the 2020 census, making Santa Ana the second most populous city in Orange County, the 13th-most populous city in California, and the 64th densest large city in the United States.

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  4. Founded in 1869, Santa Ana is located in Southern California adjacent to the Santa Ana River, 10 miles (16 km) away from the California coast. The city is part of the Los Angeles–Long Beach–Santa Ana metropolitan area which, according to the U.S. Census Bureau, is the second largest metropolitan area in the U.S., with almost thirteen ...

    • Santa Ana, CA
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  5. Santa Ana, CA is home to a population of 314k people, from which 76.4% are citizens. As of 2021, 41.7% of Santa Ana, CA residents were born outside of the country (131k people). In 2021, there were 2.34 times more Other (Hispanic) residents (149k people) in Santa Ana, CA than any other race or ethnicity.

  6. Apr 26, 2024 · Santa Ana, city, seat (1889) of Orange county, southern California, U.S. It lies at the base of the Santa Ana Mountains, on the Santa Ana River. It was explored by the Spaniard Gaspar de Portolá in 1769, and Juan Pablo Grijalva was subsequently (1801) given a land grant for the area, which he named.

    • The Editors of Encyclopaedia Britannica
  7. Aug 8, 2022 · Santa Ana is a small city situated in Orange County in Southern California's Greater Los Angeles region. Santa Ana is California's 13th most populous city and the nation's 4th most densely populated city after New York City, San Francisco, and Boston. The city also serves as the Orange Coast's chief economic and cultural hub.

  8. Santa Ana is a city in and the county seat of Orange County, California, United States. Located in the Greater Los Angeles region of Southern California, the city's population was 310,227 at the 2020 census, making Santa Ana the second most populous city in Orange County, the 13th-most populous city in California, and the 64th densest large ...

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