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  1. The history of vaccines begins before the first vaccine, with an immunizing procedure called "inoculation" by some and "variolation" by others. According to researchers, inoculation with materials from smallpox lesions to trigger immunity against smallpox dates back to antiquity in China.

  2. Apr 9, 2021 · Graham joined Jason McLellan (of Kwong's team) to adapt a structure-based approach to an RSV vaccine. They identified the prefusion conformation of the viral spike protein as highly immunogenic and created mutations to stabilize that conformation for successful use as an immunogen. This was a huge step toward the creation of a successful RSV ...

    • Anthony S. Fauci
    • 2021
  3. Jul 26, 2021 · From the first vaccine developed in 1796 against smallpox to the latest COVID-19 vaccine, there have been several vaccines that have reduced the burden of disease, with the associated mortality and morbidity.

    • Amr Saleh, Shahraz Qamar, Aysun Tekin, Romil Singh, Rahul Kashyap
    • 10.7759/cureus.16635
    • 2021
    • Cureus. 2021 Jul; 13(7): e16635.
  4. Scientific advances in the first half of the 20th Century led to an explosion of vaccines that protected against whooping cough (1914), diphtheria (1926), tetanus (1938), influenza (1945) and mumps (1948). Thanks to new manufacturing techniques, vaccine production could be scaled up by the late 1940s, setting global vaccination and disease ...

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  5. In 1961 it was hailed as 100% effective and the first measles vaccine was licensed for public use in 1963. Individual countries introduced mass vaccination programmes against measles at the national level from the 1960s on, and the first internationally focused measles immunization programmes took place in Africa from 1966.

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  6. Dec 10, 2020 · By Sandy Cohen. 6 min read. The COVID-19 vaccines coming soon to the United States and already approved in the U.K. and Canada are the fastest vaccines ever created.

  7. Edward Jenner FRS FRCPE [1] (17 May 1749 – 26 January 1823) was an English physician and scientist who pioneered the concept of vaccines and created the smallpox vaccine, the world's first vaccine. [2] [3] The terms vaccine and vaccination are derived from Variolae vaccinae ('pustules of the cow'), the term devised by Jenner to denote cowpox.

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