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  1. Jan 24, 2018 · Introduction. Invasive fungal infections (IFIs) are increasingly recognized in the expanding population of immunocompromised hosts such as transplant recipients, people receiving immunosuppressive and chemotherapeutic agents, patients with human immunodeficiency virus (HIV) infection, and individuals at the extreme of life (i.e., premature infants and the elderly) [1–4].

  2. Jul 1, 2011 · Invasive fungal infections are infections of importance and are increasing in incidence in immunocompromised hosts such as patients who have had hematopoietic stem cell and solid organ transplants. Despite our expanded antifungal armamentarium, these infections cause considerable morbidity and mortality. Indeed, certain trends have emerged in ...

  3. Jun 1, 2015 · The prevention and treatment of sepsis in the immunocompromised host present a challenging array of diagnostic and management issues. The neutropenic patient has a primary defect in innate immune ...

  4. Introduction. Older adults are at an increased risk of contracting infectious pathogens due to their declining immune system, in addition to other age-related changes throughout all body systems 1. Due to these vulnerabilities, older adults are at an increased risk of sepsis 1. Often, diagnosis and initiation of sepsis bundles are delayed due ...

  5. Apr 1, 2020 · Of patients with sepsis, 80% are initially treated in an emergency department, and the remainder develop sepsis during hospitalization for other conditions. 5 Major risk factors for developing ...

  6. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a global pandemic with over 8 million reported cases and 400 000 deaths [1, 2].Due to impaired immune defenses from both underlying disease and treatment, immunocompromised patients with respiratory virus infection are at risk of more severe infection and increased rates of bacterial and fungal superinfection compared with ...

  7. The term “septic shock” is used to describe what’s happening when a person’s blood pressure is low, oxygen delivery to vital organs is compromised, and the threat of death is imminent. About 1.7 million U.S. adult cases of sepsis occur each year, and nearly 270,000 die from the condition. Sepsis can be difficult to diagnose immediately ...