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  1. Apr 14, 2020 · How Marvel's Worst Virus Changed The X-MEN Forever. By Charles Prefore. Published Apr 14, 2020. Perhaps one of the greatest threats to the existence of X-Men's mutants, the legacy virus presented readers with a terror that transcends the medium.

  2. When Colossus' sister Illyana fell ill and died in Uncanny X-Men #303 (August 1993), he left the X-Men and joined Magneto's Acolytes, but later returned. His teammate Beast developed a cure for the virus, but in order for it to be quickly dispersed, a mutant had to sacrifice himself.

  3. Nov 22, 2020 · Published Nov 22, 2020. The Legacy Virus was a biological weapon meant to kill all mutants and the X-Men were no exception, suffering several casualties. Over the years, the X-Men have faced many threats, with each more deadly than the last.

  4. Mar 27, 2024 · First appearing in the epilogue for 1993's X-Force #18 by Fabian Nicieza and Greg Capullo, the Legacy Virus changed the X-Men forever when it was created as a deadly disease that affected the mutant population. The release of this plague saw a nearly decade-long story that killed hundreds of mutants, including fan-favorite characters like Pyro.

  5. Nov 30, 2021 · With HIV renamed “The Legacy Virus,” the multi-title storyline was an easily discernible, outspoken allegory detailing how a maligned people stands to cope with a disease ravaging its own community. The Legacy Virus wasn’t identical to HIV.

  6. May 18, 2021 · By Brandon Zachary. Published May 18, 2021. The Legacy Virus was a potentially ruinous disease for the X-Men, but Marvel's mutant plague only killed a handful of known X-Men. The Legacy Virus was introduced in the final moments of "X-Cutioner's Song," which pitted the X-Men against the time-displaced maniacal clone of Cable, Stryfe.

  7. The legacy virus was a biological weapon engineered and released by the madman Stryfe for the purpose of killing all mutants. The plague lasted for years and killed many mutants and a few humans ...

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