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  1. In people aged 60 years or older, due to a higher risk of life-threatening side effects, the vaccine should be given only when there is a significant and unavoidable risk of acquiring yellow fever infection, such as travel to an area where there is a current or periodic risk of yellow fever transmission [3, 4].

    • What is the yellow fever vaccine?
    • How does the vaccine work?
    • What are the mild side effects?
    • Are there any serious side effects?
    • Who needs the vaccine?
    • Should anyone not get it?
    • The bottom line

    Yellow fever is a potentially fatal disease caused by the yellow fever virus.

    The virus is found in parts of South America and Africa. It’s spread through the bite of mosquitos infected with the virus. It’s not transmitted from person to person.

    Some people with yellow fever only experience flu-like symptoms and recover completely after a short time. Others develop a more severe form of the infection that causes serious symptoms, such as:

    •high fever

    •vomiting

    •yellow skin (jaundice)

    The yellow fever vaccine causes your immune system to produce antibodies against the virus. It’s administered as a relatively painless injection.

    If you’re in the United States and are planning to travel to an area where yellow fever is common, you’ll need to get vaccinated at an authorized yellow fever vaccination center.

    You can find their locations here.

    Originally, a single dose was meant to last for at least 10 years. But in 2013, the World Health Organization (WHO) announced that a single injection should provide life-long immunity.

    Keep in mind that this change still isn’t reflected in the International Health Regulations, a legally-binding document put out by WHO. As a result, some countries may not accept a certificate that’s more than 10 years old.

    You can check regulations in specific countries here. You might want to call the local embassy before your trip just to be sure.

    As with almost any other medicine or vaccine, some people have a reaction to the yellow fever vaccine.

    Usually, this reaction is mild, with side effects such as:

    •fever

    •muscle aches

    •mild joint pain

    In addition, any kind of injection can cause soreness, redness, or swelling around the injection site.

    There’s a small risk of serious side effects from the yellow fever vaccine. The CDC states that this includes:

    •a severe allergic reaction, which affects about 1 in 55,000 people

    •a severe nervous system reaction, which affects about 1 in 125,000 people

    •severe illness with organ failure, which affects about 1 in 250,000

    After receiving the vaccine, keep an eye out for these symptoms of a serious allergic reaction:

    •behavior changes

    Yellow fever vaccine is recommended for the following:

    •all persons aged 9 months or older who are living in or traveling to areas of South America, Africa, or other countries where the yellow fever virus is found

    •people who are traveling to countries requiring proof of yellow fever immunization

    •anyone who might come into contact with the yellow fever virus, such as laboratory workers or healthcare professionals

    The vaccine shouldn’t be given to:

    •children younger than 9 months of age

    •adults older than 59 years of age

    •people with reduced immunity, such as people with HIV or those receiving chemotherapy

    •people who’ve had a severe reaction to egg, gelatin, or other ingredients of the vaccine

    •people who’ve had a severe allergic reaction to a previous dose of the vaccine

    Yellow fever is a serious illness, so it’s important to get vaccinated if you plan to be in an area where the virus is common.

    If you’re not sure if you should get the vaccine, talk to a doctor. They can help you weigh the benefits and risks.

    Keep in mind that the vaccine isn’t foolproof. When traveling to areas with the yellow fever virus, it’s important to still protect yourself against mosquito bites by using nets, insect repellants, and protective clothing.

    Try to stay indoors during peak times when mosquitos may bite to further lower your risk. Most species bite from dusk to dawn, but one species feeds during the daytime. Staying in air-conditioned rooms can lower your risk.

  2. Jan 15, 2019 · Some people may have an increased risk of developing a reaction to the vaccine, but may still benefit from being vaccinated. These people, or their guardians, should talk to a healthcare provider about getting vaccinated: Between 6 and 8 months old; Over 60 years old; Pregnant; Breastfeeding

  3. May 1, 2024 · Geriatric. Use of this vaccine should be limited to elderly patients older than 65 years of age who are traveling to, or living in, areas where there is yellow fever infection. Breastfeeding. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding.

  4. Apr 1, 2020 · People 60 years and older and people with weakened immune systems might be more likely to experience serious reactions to yellow fever vaccine. People sometimes faint after medical procedures, including vaccination. Tell your provider if you feel dizzy or have vision changes or ringing in the ears.

  5. Aug 10, 2021 · damage to internal organs, such as the liver or kidneys. The risk of adverse reactions may be higher in certain groups, such as people over the age of 60 years and those with severe ...

  6. A single dose provides lifelong protection for most people. The vaccine is a live, weakened form of the virus given as a single shot. Vaccine is recommended for people aged 9 months or older and who are traveling to or living in areas at risk for yellow fever virus in Africa and South America.

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