This combined with the dry, hot summer and low water tables of 1793 created the perfect breeding grounds for mosquitoes and the spread of Yellow Fever. On August 19, 1793, the first fatality of Yellow Fever, Peter Aston, became a topic of “general conversation” according to Mathew Carey, Irish-born American publisher and first hand witness ...
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Major American Epidemics of Yellow Fever (1793-1905) Share: Copy Link. Yellow fever appeared in the U.S. in the late 17th century. ... Yellow fever epidemics took more than 41,000 lives in New ...
- American Experience
Dec 01, 2006 · EDITORS: Photos available on request. ANN ARBOR—The University of Michigan’s Clements Library is exhibiting newspaper accounts, maps, engravings, minute books, pamphlets and personal letters documenting the horrendous yellow fever epidemic that struck Philadelphia in 1793, killing 5,000 people, roughly 10 percent of the city’s population, in only three months.
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Feb 05, 2016 · A series of 19th-century images depicting the development of yellow fever. | Images courtesy of Wellcome Images via Wikimedia Commons The summer of 1793 was unusually dry and hot in Philadelphia.
- Sandy Hingston
During the 1793 yellow fever epidemic in Philadelphia, 5,000 or more people were listed in the official register of deaths between August 1 and November 9.The vast majority of them died of yellow fever, making the epidemic in the city of 50,000 people one of the most severe in United States history.
The fever took a devastating toll on the city as nearly 5,000 individuals died, among them close to 400 African Americans. Above: Dead House on the Schuylkill during the yellow fever in Philadelphia in 1793, David Johnson Kennedy, Watercolor, Historical Society of Pennsylvania.
- Clinical significance
Rocky Mountain spotted fever (RMSF) is an illness caused by infection with the bacterium Rickettsia rickettsia, which is transmitted by a bite from infected ticks.
The bacterium Rickettsia rickettsia that causes Rocky Mountain spotted fever is transmitted by the bite of an infected tick. The primary vectors (the agents that transmit infection) for RMSF in the U.S. are the American dog tick (Dermacentor variabilis), the Rocky Mountain wood tick (Dermacentor andersoni), and the brown dog tick (Rhipicephalus sanguineus).
Early symptoms of Rocky Mountain spotted fever usually occur about five to 10 days following the tick bite, and include fever, nausea, vomiting, muscle pain, loss of appetite, and headache. As the disease progresses, symptoms may include rash, abdominal pain, joint pain, and diarrhea. The disease can be severe and most patients need to be hospitalized.
The disease was named Rocky Mountain spotted fever as the disease was first discovered in that part of the U.S., however there are few cases in that part of the country today. Most cases of RMSF in the U.S. occur in the southeastern part of the country, including Delaware, Maryland, Washington D.C., Virginia, West Virginia, North Carolina, South Carolina, Georgia, and Florida. The most cases of RMSF are found in North Carolina and Oklahoma. Other than Antarctica, RMSF can be found in nearly all parts of the world. The disease occurs seasonally, mostly from April through September in the US. While anyone can be infected, children under 10 years of age are at highest risk.
To diagnose Rocky Mountain spotted fever, three things a physician will look for are fever and rash, occurring a few days after a tick bite. One test for RMSF includes a biopsy of the skin rash, and another involves immunofluorescence staining of skin-tissue samples. Treatment usually begins immediately, even before test results come back, as the disease can progress rapidly.
Treatment for Rocky Mountain spotted fever includes a tetracycline (Achromycin) antibiotic, usually doxycycline (Vibramycin). This is taken per doctor's instructions until several days after the fever goes away and the patient starts to show signs of improvement. Most patients are treated for five to 10 days, even while waiting for lab test results to come back. To remove the tick, grasp it as close to the skin's surface as possible and pull upward with steady, even pressure. Do not twist the tick as this may cause the mouth parts to break off and remain in the skin. If this happens remove the remaining parts with tweezers. Contact your doctor if you are unable to remove remaining parts, or if illness occurs. Once the tick is removed, disinfect the bite with rubbing alcohol and wash hands thoroughly with soap and water.
It is believed that once a person is infected with R. rickettsia, the bacterium that causes Rocky Mountain spotted fever, they will be immune to contracting it again. However, tick-preventive measures should always be taken, as ticks can transmit other diseases. The best way to reduce the chances of getting Rocky Mountain spotted fever is to limit exposure to ticks. If you live in a tick-infested area, promptly remove all crawling or attached ticks. It may take some time to transmit the disease from the tick to the host, so prompt removal is important. While you can't completely eliminate all exposure to ticks, the following slides discuss preventive measures that can be taken to protect yourself when in tick-infested environments. Wear light-colored clothing to allow you to more easily see ticks on your clothes. Keep ticks out by tucking your pant legs into your socks so ticks cannot crawl up your legs. Use repellants to discourage ticks from attaching to you. Permetrin is a repellant that can be sprayed on clothing and shoes that will last several days. DEET (n, n-diethyl-m-toluamide) is a repellant that can be applied directly to the skin, but only lasts a few hours. Use caution when applying DEET to children, as it may cause adverse reactions. Check with your child's pediatrician about what repellants to use safely on your child. Check your children and pets for ticks after you have been in a tick-infested area as both can carry ticks into the house that will attach to a person later. Pay special attention to their hair and remove any ticks promptly. Remove ticks safely. Use fine-tipped tweezers or specially-made notched tick extractors. Protect hands with paper towels or latex gloves. Do not remove ticks with bare hands. Never squeeze or crush the body of the tick because the fluids may contain the infectious bacterium. If the tick is accidentally crushed or punctured and tick fluids get on the skin, disinfect with rubbing alcohol or iodine. Limiting exposure to ticks remains the most effective way to prevent tickborne disease. However, application of acaricides (chemicals that kill ticks and mites) and control of tick habitats (for example, leaf litter and brush) have been effective in small-scale trials. Other methods being developed include applying acaricides to animal hosts by using baited tubes, boxes, and feeding stations in tick-infested areas. Fungi, parasitic nematodes, and parasitic wasps may also help with tick-control efforts. Community-based tick management strategies may be an effective public-health response to reduce the incidence of tick-borne infections.
Rocky Mountain spotted fever. This disease is caused by Rickettsia rickettsii and is transmitted by a number of different ticks. Despite its geographical title, Rocky Mountain spotted fever is ...