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  1. Apr 20, 2023 · Treatment will likely start while your provider waits for the results of one or more laboratory tests to identify the Yersinia pestis bacteria. Samples for tests may come from: Fluid from buboes. Blood. Mucous from the lungs. Fluid surrounding the brain and spinal cord.

  2. Jul 15, 2021 · * Dual therapy with two distinct classes of antimicrobials should be used for initial treatment of patients with severe pneumonic or septicemic plague and patients infected after intentional release of Yersinia pestis.

  3. Dec 26, 2017 · FIG 1. Transmission, diagnosis, treatment, and prevention of plague. Plague is a zoonotic disease caused by Yersinia pestis, whose natural life cycle includes rodents and fleas. Plague can be transmitted to humans through the bite of an infected flea, close contact with animals suffering from plague, or respiratory droplets of an infected animal.

  4. Feb 25, 2022 · The incubation period for bubonic plague is usually 2 to 8 days. If bubonic plague is untreated, Yersinia pestis can invade the bloodstream and spread rapidly, causing sepsis; if the lungs are seeded, pneumonia can develop. Sepsis and pneumonia can also be primary manifestations of plague.

  5. Aug 6, 2021 · Plague is a disease that affects humans and other mammals. It is caused by the bacterium, Yersinia pestis. Humans usually get plague after being bitten by a rodent flea that is carrying the plague bacterium or by handling an animal infected with plague. Plague is infamous for killing millions of people in Europe during the Middle Ages.

  6. Oct 31, 2022 · Daniel J Sexton, MD. Deputy Editor: Allyson Bloom, MD. Literature review current through: Feb 2024. This topic last updated: Oct 31, 2022. INTRODUCTION. In the genus Yersinia, three species are important human pathogens: Yersinia pestis, Yersinia enterocolitica, and Yersinia pseudotuberculosis.

  7. Jul 7, 2022 · Plague is caused by the bacteria Yersinia pestis, a zoonotic bacteria usually found in small mammals and their fleas. People infected with Y. pestis often develop symptoms after an incubation period of one to seven days. There are two main clinical forms of plague infection: bubonic and pneumonic.

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