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      • The EBOV genome is a single-stranded RNA, approximately 19,000 nucleotides long. It encodes seven structural proteins: nucleoprotein (NP), polymerase cofactor (VP35), (VP40), GP, transcription activator (VP30), VP24, and RNA-dependent RNA polymerase (L).
      en.wikipedia.org › wiki › Zaire_ebolavirus

      Zaire ebolavirus - Wikipedia

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  3. www.ncbi.nlm.nih.gov › pmc › articlesStructural and Functional Aspects of Ebola Virus Proteins

    Oct 15, 2021 · Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented, single-stranded RNA that contains seven genes: (a) nucleoprotein (NP), (b) viral protein 35 (VP35), (c) VP40, (d) glycoprotein (GP), (e) VP30, (f) VP24, and (g) RNA polymerase (L). All genes encode for one protein each except GP, producing three pre ...

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    • Table 1

      Ebola virus (EBOV), member of genus Ebolavirus, family...

  4. en.wikipedia.org › wiki › Zaire_ebolavirusZaire ebolavirus - Wikipedia

    It encodes seven structural proteins: nucleoprotein (NP), polymerase cofactor (VP35), (VP40), GP, transcription activator (VP30), VP24, and RNA-dependent RNA polymerase (L). [10]

  5. www.ncbi.nlm.nih.gov › pmc › articlesEbolavirus glycoprotein structure and mechanism of entry - PMC

    Zaire ebolavirus glycoprotein glycosylation N -linked biantennary complex-type glycans (Gal 2 Man 3 GlcNAc 4 ) are modeled as yellow space-filling spheres onto the Zaire ebolavirus GPΔmucΔtm structure at predicted glycosylation sites: Asn40, Asn204, Asn228, Asn238, Asn257, Asn268 and Asn563.

    • Jeffrey E Lee, Erica Ollmann Saphire
    • 10.2217/fvl.09.56
    • 2009
    • 2009

  6. www.nature.com › articles › s41586/022/05271-2Structure of the Ebola virus polymerase complex | Nature

    Sep 28, 2022 · Structural analysis revealed that Ebola virus L possesses a filovirus-specific insertion element that is essential for RNA synthesis, and that VP35 interacts extensively with the N-terminal...

  7. www.nature.com › articles › s41586/018/0630-0Cryo-EM structure of the Ebola virus nucleoprotein–RNA ...

    Oct 17, 2018 · Nature - Near-atomic resolution cryo-electron microscopy structures of the Zaire ebolavirus nucleoprotein indicate a complex transition from the RNA-free to RNA-bound forms of the...

    • Yukihiko Sugita, Hideyuki Matsunami, Yoshihiro Kawaoka, Takeshi Noda, Matthias Wolf
    • 2018

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  9. www.ncbi.nlm.nih.gov › pmc › articlesUnderstanding of Zaire ebolavirus–human protein interaction ...

    Mar 7, 2020 · The genome size of the virus is approximately 19 kb and encodes seven structural proteins such as, envelop glycoprotein (GP), membrane-associated virion protein (VP24), transcription activator (VP30), polymerase cofactor (VP35), matrix protein (VP40), nucleoprotein (NP) and RNA dependent RNA polymerase (L) [ 49 ].

  10. www.nejm.org › doi › fullEbola | New England Journal of Medicine

    May 6, 2020 · Filoviruses replicate in the cytoplasm of their target cells. 16-18 Viral particles attach to the cell surface through the binding of glycoprotein to multiple attachment factors, such as C-type...

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