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  2. Jan 13, 2020 · In adult outpatients with moderate to severe ulcerative colitis, the AGA recommends using infliximab, adalimumab, golimumab, vedolizumab, tofacitinib, or ustekinumab over no treatment. (Strong recommendation, moderate quality evidence)

    • Gastroenterology

      Combined oral and enema treatment with Pentasa (mesalazine)...

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      ulcerative colitis, the AGA recommends using infliximab,...

  3. A comprehensive assessment of severity of UC should include predictors of an aggressive disease course, need for colectomy, and response to therapies. Several prospective cohorts have examined the role of clinical parameters, genetics, and serologic markers in predicting the need for colectomy in UC ( 69,70 ).

  4. Aug 17, 2020 · The choice of treatment for ulcerative colitis is generally based on the pattern of involvement of the disease and the degree of its clinical activity (figure 1). Mesalamine, also known as 5-aminosalicylic acid (5-ASA), is a pillar of pharmacotherapy for ulcerative colitis.

    • Torsten Kucharzik, Sibylle Koletzko, Klaus Kannengiesser, Axel Dignass
    • 10.3238/arztebl.2020.0564
    • 2020
    • 2020/08
  5. Jan 26, 2024 · Therapies can be grouped as induction therapies (ie, relatively rapid onset of action) and maintenance therapies (ie, appropriate for long-term use). Some therapies (eg, biologic agents, small molecules) are used for both induction and maintenance of remission.

  6. Endoscopic procedures with tissue biopsy are the only way to definitively diagnose ulcerative colitis. Other types of tests can help rule out complications or other forms of inflammatory bowel disease, such as Crohn's disease.

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