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  1. All roles for the series are cast without the characters' races being pre-specified, in keeping with Rhimes' vision of diversity. The series' protagonist, Meredith Grey, is portrayed by Ellen Pompeo. Pompeo starred in the leading role in Moonlight Mile, which led to her being cast as Meredith.

  2. Grey's Anatomy: Created by Shonda Rhimes, Michelle Lirtzman. With Ellen Pompeo, Chandra Wilson, James Pickens Jr., Justin Chambers. A drama centered on the personal and professional lives of five surgical interns and their supervisors.

  3. Learn more about the full cast of Grey's Anatomy with news, photos, videos and more at TV Guide.

  4. Grey's Anatomy Cast. Follow Grey's Anatomy: Meet the cast and hosts of Grey's Anatomy, read their bios, top moments, and view their photos, videos and more at ABC.com.

  5. Series Cast 126. Ellen Pompeo. Meredith Grey (20 Episodes) Chandra Wilson. Miranda Bailey (20 Episodes) James Pickens Jr. Richard Webber (20 Episodes) Kevin McKidd. Owen Hunt (20 Episodes)

  6. Series Cast 120. Ellen Pompeo. Meredith Grey (20 Episodes) Chandra Wilson. Miranda Bailey (20 Episodes) James Pickens Jr. Richard Webber (20 Episodes) Kevin McKidd. Owen Hunt (20 Episodes)

  7. Patrick Dempsey is well-known for his portrayal of Dr. Derek Shepherd on the hit ABC series, GREY'S ANATOMY. His performance earned him a 2007 Screen Actors Guild Award and was nominated in 2006 and 2007 for a Golden Globe for Best Performance by an Actor in a Television Series - Drama.

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