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  1. David F. Savage Dave is an Associate Professor in the Department of Molecular & Cell Biology at the University of California, Berkeley and an Investigator in the Howard Hughes Medical Institute. Dave was born and raised in rural Iowa. He continues to help manage his family’s farm, which was recognized in 2010 as an Iowa Heritage Farm.

  2. David Savage is an associate professor of biochemistry, biophysics, and structural biology in the Department of Molecular and Cell Biology. The goal of the Savage Lab is to understand how protein machinery – including both enzymes and compartmentalization - facilitates the biochemistry of the cell.

  3. Jun 8, 2022 · David Savage was determined to walk again after his traumatic injury. ( ABC News: Dave Maguire ) By 2020, despite years of work and trying numerous devices, he was still unable to take even a few ...

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    • Applying The Full Force of CRISPR
    • Edited Crops For A Changing World
    • High-Throughput Screening
    • From Lab to Field

    Capturing and sequestering carbon from the atmosphere is key to mitigating some of the worst consequences of climate change. But the planet is already experiencing the climatic effects of the carbon dioxide, methane and nitrogen oxides we’ve put into the atmosphere since the Industrial Revolution began. These cause increased drought events, alterna...

    The CRISPR revolution started only a decade ago, in April 2012, when UC Berkeley researchers discovered how to redesign a protein at the heart of the immune systems of many bacteria to target and cut DNA in any organism, plant or animal. That work was published 10 years ago today (June 28) in the journal Science . Today, the CRISPR-Cas9 enzyme is k...

    CRISPR alone would be insufficient to accelerate plant breeding without a faster way to screen cells that have been edited — a high-throughput method to determine whether knocking out a gene or targeting a promoter to up- or down-regulate its associated gene has the desired effect. Rather than editing plant cells directly — from a root or leaf, for...

    The IGI researchers have already made impressive progress. Niyogi has been testing genetically modified crops in fields at the University of Illinois-Urbana Champaign, showing that it’s possible to get plants to grow well on 25% less water and to increase leaf carbon dioxide uptake, as well as plant productivity, by about 15%. He’s achieved this by...

  5. David G. Savage has covered the Supreme Court and legal issues for the Los Angeles Times in the Washington bureau since 1986. He has covered the Senate confirmation hearings for all of the current ...

    • david.savage@latimes.com
    • Staff Writer
  6. 2012. Engineering cyanobacteria to synthesize and export hydrophilic products. H Niederholtmeyer, BT Wolfstädter, DF Savage, PA Silver, JC Way. Applied and environmental microbiology 76 (11), 3462-3466. , 2010.

  7. From 2007 to 2011, I was a Life Sciences Research Foundation fellow with Pamela Silver at Harvard Medical School. Research in the Savage Lab focuses on understanding and engineering two of the most compelling biochemical systems found in nature: genome editing and carbon fixing enzyme machineries. Ultimately, this works seeks to develop ...

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