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Jul 20, 2020 · The 719-member-strong Yangshan virus assemblage is the sister clade to the expansive class Alsuviricetes and consists of viruses with simple genomes that typically encode only...
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Oct 13, 2022 · Specifically, the family Cystoviridae, which migrated from Duplornaviricota to Pisuviricota in the current RdRP phylogeny, forms a strongly supported branch with picobirnaviruses and partitiviruses (double-stranded RNA [dsRNA] families embedded in the midst of the +ssRNA viruses [Figure 2)).
Apr 4, 2023 · To see if these unclassified sequences form a separate clade, and how phylogenetically different they are from sequences with a strong match to the Totiviridae pHMM, we compared the 22 sequences with classified sequences.
Apr 8, 2022 · The vast majority of known RNA viruses lie within the realm Riboviria and possess a universally conserved RNA-dependent RNA polymerase (RdRP) gene [ 16 ]. This gene can be used to identify viral...
Sep 1, 2022 · By combining RdRp-specific hidden Markov models (HMMs) and structural comparisons, we show that RdRp-scan can efficiently detect RdRp sequences with identity levels as low as 10 per cent to those from known viruses and not identifiable using standard sequence-to-sequence comparisons.
Jan 5, 2024 · Among the identified viruses, we could detect (1) two new negative sense ssRNA viruses related to the yueviruses, (2) the first example of permuted RdRp in a virus infecting fungi/oomycetes, (3) a new group of bipartite dsRNA viruses showing evidence of recent bi-segmentation and concomitantly, a possible duplication event bringing a bipartite ...
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Which clade is a pisuviricota RdRp?
Does phylum pisuviricota have multiple groups of +ssRNA viruses?
How many RdRp sequences are there in the Totiviridae PHMM?
How many RdRPs are there in kitrinoviricota (brandma-like) viruses?
The ORF of dsRNA 1 encodes the RNA dependent RNA polymerase (RdRP) responsible for the replication of the virus. The RdRP of polymycoviruses belongs to the protein family RdRP_1 (Pfam PF00680) and has three conserved motifs (MSDITKWDANMC, YGCMPSGSFYTSLVNTTGNNL and YGDNQLFSEHL) typical of RdRPs in its catalytic domain (Figure 2 Polymycoviridae ).
